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Research

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Protein Formulation

High concentration antibody formulations incl. suspensions


Protein stabilization


Computer modeling of protein behavior in solution and at interfaces


New surfactants for formulation of biologics

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Lyophilization / Frozen Bulk

Process understanding including heat transfer and new characterization tools


Scale down of bulk freezing


Stable lyophilisates of proteins, nanoparticles and ATMPs


Understanding protein and particle behavior in the freeze-concentrate

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Protein Aggregation

Driving mechanisms incl. protein-protein-interactions and interface effects


Formulation and mutation / variant effects on aggregation


Protein adsorption to interfaces including air, silicone oil and processing materials


New methods for aggregation analysis