H. Zipse, 2nd ed., RSC, 2023.
About this book
The first edition of "Reactivity and Mechanism in Organic Chemistry" was published in 2019 as a companion text for the lecture course with the same name in the LMU Bachlor "Chemistry and Biochemistry" program. Completely revised and updated, the 2nd Edition of "Reactivity and Mechanism in Organic Chemistry" published in 2022 by the RSC is an ideal introduction to the quantitative description of organic reactivity for students in undergraduate and masters chemistry programmes. The book proceeds logically from qualitative molecular orbital theory as a tool for the description of bonding phenomena to combining this with thermochemical data to rationalise concepts such as molecular strain and hyperconjugation. Next, transition state theory, for examining organic reactivity phenomena, is introduced and its relation to energy surfaces and simple rate equations is discussed. On this basis more specific reactivity concepts commonly used in organic chemistry are explored such as the Bell–Evans–Polanyi principle, Marcus theory, HSAB principle, Hammett correlations, the Mayr–Patz equation, and FMO theory. How these reactivity models are applied is demonstrated for pericyclic reactions and selected rearrangement reactions involving transient intermediates such as radicals, diradicals, or carbocations, and for reactions involving classical electrophile/nucleophile combinations.
Additional Material, Comments and Corrections
for chapter 1: "Structure and Bonding in Organic Molecules"
for chapter 2: "Reactivity Models in Organic Chemistry"
for chapter 3: "Pericyclic Reactions"