Robert J. Mayer
M. Sc., Dr. rer. nat.

11/2015-01/2021

AK Prof. Mayr/Dr. Ofial 
Dept. Chemie 
Ludwig-Maximilians-Universität München 
Butenandtstr. 5-13 (Haus F) 
81377 München 

Awards
Award of the Dr. Klaus Römer-Stiftung for MSc students (2017).
Award of the Dr. Klaus Römer-Stiftung for PhD students (2020).
Dissertation
Reactivity of oxygen and sulfur nucleophiles and basicity scales toward heteroatom Lewis acids
DOI: 10.5282/edoc.26279
Publications
Resolving the Mechanistic Complexity in Triarylborane-Induced Conjugate Additions
R. J. Mayer,* N. Hampel, A. R. Ofial, H. Mayr, ACS Catal., 2022, 12, 15298-15309.
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Quantification of the Electrophilicities of Diazoalkanes: Kinetics and Mechanism of Azo Couplings with Enamines and Sulfonium Ylides
L. Li, R. J. Mayer, D. S. Stephenson, P. Mayer, A. R. Ofial, H. Mayr, Chem. Eur. J. 2022, 28, e202201376.
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Epigenetic anti-cancer treatment with a stabilized carbocyclic Decitabine analogue
F. R. Traube, N. F. Brás, W. P. Roos, C. C. Sommermann, T. Diehl, R. J. Mayer, A. R. Ofial, M. Müller, H. Zipse, T. Carell, Chem. Eur. J. 2022, 28, e202200640.
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An Overlooked Pathway in 1,3-Dipolar Cycloadditions of Diazoalkanes with Enamines
L. Li, P. Mayer, D. S. Stephenson, A. R. Ofial, R. J. Mayer,* H. Mayr,* Angew. Chem. Int. Ed., 2022, 61, e202117047.
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Quantification of the Lewis Basicities and Nucleophilicities of 1,3,5-Tris(dialkylamino)benzenes
G. Micheletti, R. J. Mayer, S. Cino, C. Boga, A. Mazzanti, A. R. Ofial, H. Mayr, Eur. J. Org. Chem. 2021, 6347-6357.
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Electrophilic Reactivities of Cyclic Enones and α,β-Unsaturated Lactones
R. J. Mayer, P. W. A. Allihn, N. Hampel, P. Mayer, S. A. Sieber, A. R. Ofial, Chem. Sci. 2021, 12, 4850-4865.
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Lewis Acidic Boranes, Lewis Bases, and Equilibrium Constants: A Reliable Scaffold for a Quantitative Lewis Acidity/Basicity Scale
R. J. Mayer, N. Hampel, A. R. Ofial, Chem. Eur. J. 2021, 27, 4070-4080.
[download]
From Carbodiimides to Carbon Dioxide: Quantification of the Electrophilic Reactivities of Heteroallenes
Z. Li, R. J. Mayer, A. R. Ofial, H. Mayr, J. Am. Chem. Soc. 2020, 142, 8383-8402.
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Predicting Absolute Rate Constants for Huisgen Reactions of Unsaturated Iminium Ions with Diazoalkanes
Voraussage absoluter Geschwindigkeitskonstanten von Huisgen-Reaktionen ungesättigter Iminium-Ionen mit Diazoalkanen
J. Zhang, Q. Chen, R. J. Mayer, J.-D. Yang, A. R. Ofial, J.-P. Cheng, H. Mayr,
Angew. Chem. 2020, 132, 12628-12634; Angew. Chem. Int. Ed. 2020, 59, 12527-12533.

[download]
Electrophilic Reactivities of Vinyl p-Quinone Methides
A. Eitzinger, R. J. Mayer, N. Hampel, P. Mayer, M. Waser, A. R. Ofial, Org. Lett. 2020, 22, 2182-2186.
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Lewis Acidity Scale of Diaryliodonium Ions toward Oxygen, Nitrogen, and Halogen Lewis Bases
R. J. Mayer,* A. R. Ofial, H. Mayr, C. Y. Legault,* J. Am. Chem. Soc. 2020, 142, 5221-5233.
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Nucleophilicity of Glutathione: A Link to Michael Acceptor Reactivities
Nucleophilie von Glutathion als Bindeglied zur Reaktivität von Michael-Akzeptoren
R. J. Mayer, A. R. Ofial, Angew. Chem. Int. Ed. 2019, 58, 17704-17708; Angew. Chem. 2019, 131, 17868-17872.
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Ambident Reactivity of Phenolate Anions Revisited: A Quantitative Approach to Phenolate Reactivities
R. J. Mayer, M. Breugst, N. Hampel, A. R. Ofial, H. Mayr, J. Org. Chem. 2019, 84, 8837-8858.
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Biomimetic Approach Toward Enterocin and Deoxyenterocin
A. Rizzo, R. J. Mayer, D. Trauner, J. Org. Chem. 2019, 84, 1162-1175.
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Synthesis, Structure and Properties of Amino-Substituted Benzhydrylium Ions - a Link Between Ordinary Carbocations and Neutral Electrophiles
R. J. Mayer, N. Hampel, P. Mayer, A. R. Ofial, H. Mayr, Eur. J. Org. Chem. 2019, 412-421.
[download]
Intramolecular Hydrogen-Bonding Modulates the Nucleophilic Reactivity of Ammonium-Peroxycarboxylates
R. J. Mayer, A. R. Ofial, Eur. J. Org. Chem. 2018, 6010-6017.
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Nucleophilic Reactivities of Bleach Reagents
R. J. Mayer, A. R. Ofial, Org. Lett. 2018, 20, 2816-2820.
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Which Factors Control the Nucleophilic Reactivities of Enamines?
D. S. Timofeeva, R. J. Mayer, P. Mayer, A. R. Ofial, H. Mayr, Chem. Eur. J. 2018, 24, 5901-5910.
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Solvation Accounts for the Counter-Intuitive Nucleophilicity Ordering of Peroxide Anions
R. J. Mayer, T. Tokuyasu, P. Mayer, J. Gomar, S. Sabelle, B. Mennucci, H. Mayr, A. R. Ofial, Angew. Chem. Int. Ed. 2017, 56, 13279-13282.
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Methoxyphenyl Substituted Bis(picolyl)phosphines and Phosphine Oxides
C. Hettstedt, M. Unglert, R. J. Mayer, A. Frank, K. Karaghiosoff, Eur. J. Inorg. Chem. 2016, 1405-1414.
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Synthesis of 2-Phosphaindolizine and [1,3]Azaphospholo[1,5-a]quinoline
C. Hettstedt, R. J. Mayer, J. F. Martens, S. Linert, K. Karaghiosoff, Eur. J. Inorg. Chem. 2016, 726-735.
[download]