Prof. Dr. Franz Bracher Chair of Pharmaceutical/Medicinal Chemistry
Address
Prof. Dr. Franz Bracher
Department Pharmazie
- Zentrum für Pharmaforschung -
Ludwig-Maximilians-Universität München
Butenandtstr. 7, Haus C
81377 München
Germany
Inhibitors of ergosterol and cholesterol biosynthesis as new drugs
Development of new, selective kinase inhibitors
Short CV
Studied pharmacy at the LMU Munich
1986 PhD in Pharmaceutical Chemistry, LMU Munich
1986-1987 Postdoctoral Researcher at the Department of Organic Chemistry, University of Geneve/Switzerland
1991 Habilitation, University of Marburg
1992-1997 C3 Professor, University of Braunschweig
Since 1997 C4 Professor for Pharmaceutical Chemistry, LMU Munich
Key publications
M. König. C. Müller, F. Bracher: Stereoselective synthesis of a new class of potent and selective inhibitors of human Δ8,7-sterol isomerase Bioorg. Med. Chem.21, 1925-1943 (2013)
K. Huber K, L. Brault, O. Fedorov, C. Gasser, P. Filippakopoulos, A. N. Bullock, D. Fabbro, J. Trappe, J. Schwaller, S. Knapp, F. Bracher: 7,8-Dichloro-1-oxo-β-carbolines as a versatile scaffold for the development of potent and selective kinase inhibitors with unusual binding modes, J. Med. Chem.55, 403-413 (2012)
K. Huber, J. Schemies, U. Uciechowska, J. M. Wagner, T. Rumpf, F. Lewrick, R. Süss, W. Sippl, M. Jung, F. Bracher: Novel 3-arylidene-indolin-2-ones as inhibitors of NAD+-dependent histone deacetylases (sirtuins), J. Med. Chem.53 , 1383 (2010)