Biomolecular structure, dynamics, assembly and interactions
AAA proteins, p97/VCP/Cdc48
Hepatitis B virus
Kurzlebenslauf
Study of Chemistry (Diploma), University of Göttingen (Germany)
2013 Dr. sc., ETH Zurich (Switzerland)
2013-2017 Postdoc, University of Toronto (Canada)
2018- Emmy Noether research group leader, Technical University of Munich (Germany)
Since 2022 Professor, LMU Munich
Wichtige Publikationen
Z.H. Taji, P. Bielytskyi, M. Shein, M.A. Sani, S. Seitz, A.K. Schütz, Transient RNA Interactions Leave a Covalent Imprint on a Viral Capsid Protein. Journal of the American Chemical Society 2022. https://doi.org/10.1021/jacs.1c12439
S. Rydzek, M. Shein, P. Bielytskyi, A.K. Schütz, Observation of a Transient Reaction Intermediate Illuminates the Mechanochemical Cycle of the AAA-ATPase P97. Journal of the American Chemical Society2020. https://doi.org/10.1021/jacs.0c03180
S. Seitz, J. Habjanič, A.K. Schütz, R. Bartenschlager, The Hepatitis B Virus Envelope Proteins: Molecular Gymnastics Throughout the Viral Life Cycle. Annual review of virology2020. https://doi.org/10.1146/annurev-virology-092818-015508.
A.K. Schuetz, L.E. Kay, A Dynamic Molecular Basis for Malfunction in Disease Mutants of P97/VCP. Elife2016. https://doi.org/10.7554/elife.20143
A.K. Schütz, T. Vagt, M. Huber, O.Y. Ovchinnikova, R. Cadalbert, J. Wall, P. Güntert, A. Böckmann, R. Glockshuber, B.H. Meier, Atomic-Resolution Three-Dimensional Structure of Amyloid β Fibrils Bearing the Osaka Mutation. Angewandte Chemie 2015. https://doi.org/10.1002/anie.201408598