Sequential Pore Wall Modiﬁcation in a Covalent Organic Framework
for Application in Lactic Acid Adsorption
In this report, we describe the synthesis and postsynthetic modiﬁcation of the stable β -ketoenamine TpBD(NH2)2 covalent organic framework (COF), having primary amine groups integrated into the pore walls. For this purpose we initially synthesized the nitro version of this COF, TpBD(NO2)2 . Afterward, TpBD(NO2)2 was reduced to aﬀord the desired framework having primary amine functionality. We demonstrate the accessibility of the primary amine groups and the robustness of the framework by a second modiﬁcation step, the aminolysis of acetic anhydride, to obtain the corresponding amide form TpBD(NHCOCH3)2. Taking advantage of the high stability of these frameworks under acidic conditions, we study the liquid-phase adsorption of lactic acid, revealing the strong impact of a pore wall modiﬁcation on the adsorption performance.
Workshop : „Biomedical Potentials of Inorganic Nanomaterials“
On the issue of „Biomedical Potentials of Inorganic Nanomaterials“, the LMU and Fudan University organized a German-Chinese Young Researcher Workshop in Shanghai. Dr. Stefan Wuttke and his colleague Dr. Rongquin Huang from the Department of Pharmacy, Fudan University – invited various scientists from the fields of pharmacy, chemistry, medicine and biophysics. The goal was an academic knowledge exchange between researchers and especially young researchers from China and Germany.
Switch-on fluorescence of a perylene dye functionalized
metal-organic framework via postsynthetic modification
In this report, we have demonstrated that linker containing perylene dye can be used as a small doping fraction for the synthesis of fluorescent MIL-101(Al)-NH2 material. This work is an important contribution to assemble structures from linkers with different functional groups but unchanged length of the linker and consequently unaltered connectivity. Importantly this powerful functionalization approach was used for the first time to introduce a sophisticated linker with a specific property. Although the incorporation of the dye linker inside the MOF scaffold was successful, the material initially does not exhibit any fluorescence. The fluorescence can be switched-on by postsynthetic modification of these groups. Depending on the concentration of the incorporated dye, different fluorescence emission spectra could be observed due to isolated chromophores at low concentration and chromophores in close proximity at higher concentrations.