Virus LMU CENS BIN

Biophysikalische Chemie / Molekulare Biophysik

Syllabus



I. Lecture: 20.10.2016

  Introduction: Biophysical Chemistry and Molecular Biophysics


II. Lecture: 20,27.10.2016

  Introduction to Important Methods/Microscopy

  1. Light Microscopy
  2. Confocal Microscopy
  3. Scanning Tunneling Microscopy
  4. Electron Microscopy

III. Lecture: 3.11.2016

  Fluorescence Microscopy

  1. Fluorescence
  2. Single-molecule methods

IV. Lecture: 10.11.2016

  Diffusion

  1. Basic Assumptions of Diffusion
  2. Fick's 1st and 2nd Law

V. Lecture: 10,17.11.2016

  Fluorescence Correlation Spectroscopy

  1. Poisson Distribution
  2. Autocorrelation Function
  3. Cross-Correlation
  4. Capabilities of FCS

VI. Lecture: 24.11.2016

  Protein Stability and Folding

  1. Hydrogen Bonding
  2. Conformational Entropy
  3. Hydrophobic Effect
  4. Levinthal's Paradox
  5. Protein Folding Funnel
  6. spFRET Measurements of Protein Refolding
  7. Unfolding of Titan

VII. Lecture: 1.12.2016

  Conformational Substates

  1. Fluctuation Dissipation Theorem
  2. Theoretical and Experimental Evidence

VIII. Lecture: 8.12.2016

  Protein Interactions and Reactions

  1. Unimolecular and Bimolecular Reactions
  2. Michaelis-Menten Model
  3. Allosteric Effects
  4. Reaction Theory

IX. Lecture: 15.12.2016

  Molecular Motors

  1. Properties of Molecular Motors
  2. Difference between nanomotors and macroscopic motors
  3. Mechanochemistry
  4. Myosin

X. Lecture: 22.12.2016

  DNA and RNA

  1. Polymer Chain Models
  2. Optical Tweezers

XI. Lecture: 12.1.2017

  DNA Interactions

  1. DNA-Protein Interactions
  2. Proofreading
  3. Anisotropy
  4. DNA Polymerase I
  5. RNA Polymerase

XII. Lecture: 19.1.2017

  Lipids and Membranes

  1. Structure and Function of Lipids
  2. Membrane Formation
  3. Membrane Properties
  4. Membrane Proteins

XIII Lecture: 26.1.2017

  Membrane Transport and Electrochemical Potential

  1. Passive and Active Transport
  2. Na-K Pump
  3. Patch-Clamp Technique
  4. Gated Ion Channels
  5. Synapses

XIV Lecture: 2.2.2017

  Energy and Organization in Living Cells

  1. Energy Update and Storage in Cells
  2. Coupled Reactions
  3. Glycolysis
  4. Cytric Acid Cycle
  5. Oxidative Phosphorylation
  6. Photosynthesis

XV Lecture: 9.2.2017

  Revision Lecture


Klausur: 24.2.2017 - from 08:00-10:00 in the Liebig Lecture Hall


Nachholklausur: 13.4.2017 - from 8:00-10:00 in the Buchner Lecture Hall



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