Landshamer, S., Höhn, M., Barth, N., Duvezin-Caubet, S., Schwake, G., Tobaben, S., Kazhdan, I., Becattini, B., Zahler, S., Vollmar, A., Pellecchia, M., Reichert, A., Plesnila, N., Wagner, E., Culmsee, C.
(2008)
Bid-induced release of AIF from mitochondria causes immediate neuronal cell death,
Cell Death Differ. 2008 Oct;15(10):1553-63
Wagner, E.
(2007)
Advances in cancer gene therapy: tumor-targeted delivery of therapeutic pDNA, siRNA, and dsRNA nucleic acids.J. BUON 12, S77-S82.
Plesnila, N., von Baumgarten, L., Retiounskaia, M., Engel, D., Ardeshiri, A., Zimmermann, R, Hoffmann, F., Landshamer, S., Wagner, E., Culmsee, C.
(2007)
Delayed neuronal death after brain trauma involves p53-dependent inhibition of NF-kB transcriptional activity.Cell Death Differ. 14, 1529-1541
Gaedtke, L., Thoenes, L., Culmsee, C., Mayer, B., Wagner, E.
(2007)
Proteomic analysis reveals differences in protein expression in spheroid versus monolayer cultures of low passage colon carcinoma cells.J. Proteome Res. 6, 4111-4118
Ogris, M., Kotha, A., Tietze, N., Wagner, E., Palumbo, F.S., Giammona, G., Cavallaro, G.
(2007)
Novel Biocompatible Cationic Copolymers Based on Polyaspartylhydrazide Being Potent as Gene Vector on Tumor Cells.Pharm. Res. 24(12), 2213-2222
Knorr, V., Allmendinger, L., Walker, G. F., Paintner, F. F., Wagner, E.
(2007)
An acetal based PEGylation reagent for pH-sensitive shielding of DNA polyplexesBioconjug. Chem. 18(4), 1218-1225.
Ruß, V., Wagner, E.
(2007)
Cell and tissue targeting of nucleic acids for cancer gene therapyPharm. Res. 24(6), 1047-1057.
Tarcha, P.J., Pelisek, J., Merdan, T., Waters, J., Cheung, K., von Gersdorff, K., Culmsee, C., Wagner, E.
(2007)
Synthesis and characterization of chemically condensed oligoethylenimine containing beta-aminopropionamide linkages for siRNA deliveryBiomaterials 28(25), 3731-3740.
Gaedtke, L., Pelisek, J., Lipinski, K. S., Wrighton, C. J., Wagner, E.
(2007)
Transcriptionally targeted nonviral gene transfer using a ß-catenin/TCF-dependent promoter in a series of different human low passage colon cancer cellsMol. Pharmaceutics 4(1), 129-139.
Meyer, M., Wagner, E.
(2006)
Recent Developments in the Application of Plasmid DNA-Based Vectors and Small Interfering RNA Therapeutics for CancerHuman Gene Ther. 17, 1062-1076.
Culmsee, C., Gasser, E., Hansen, S., Tonn, J.C., Wagner, E., Goldbrunner, R.
(2006)
Effects of Raf-1 siRNA on human cerebral microvascular endothelial cells: A potential therapeutic strategy for inhibition of tumor angiogenesisBrain Research 1125, 147-154.
DeRouchey, J., Walker, G. F., Wagner, E., Rädler, J.O.
(2006)
Decorated Rods: A 'Bottom-Up' Self-Assembly of Monomolecular DNA ComplexesJ. Phys. Chem. 110, 4548-4554.
Prasmickaite, L., Hellum, M., Kaalhus, O., Hogset, A., Wagner, E., Berg, K.
(2006)
of Transgenes Controlled by the Heat-Shock Protein 70 PromoterPhotochemistry Photobiology 82, 809-816.
Culmsee, C., Zhu, C., Landshamer, S., Becattini, B., Wagner, E., Pellechia, M., Blomgren, K., Plesnila, N.
(2005)
Polymerase and Bid Mediates Neuronal Cell Death after Oxygen–Glucose Deprivation and Focal Cerebral IschemiaJ. Neuroscience 25, 10262–10272.
Zwiorek, K., Klöckner, J., Wagner, E., Coester, C.
(2005)
Gelatin nanoparticles as a new and simple gene delivery systemJ Pharm Pharm Sci. 7, 22-8.
Couvreur, P., Braguer, D., Crommelin, D.J.A., Duchene, D., Engels, J.W., Kerr, D.J., Krogsgaard-Larsen, P., Meijer, D.K., Paoletti, R., Wagner, E.
(2005)
Contribution of academic research to discovery and development of medicines: current status and future opportunitiesEur J Pharm Sci 24, 245-252.
Kircheis, R., Wagner, E.
(2003)
Technology evaluation: TNFerade, Gen VecCurr. Opin. Mol. Ther. 5(4), 437-447.
Magin-Lachmann, C., Kotzamanis, G., DAiuto, L., Wagner, E., Huxley, C.
(2003)
Retrofitting BACs with G418 resistance, luciferase, and oriP and EBNA-1 new vectors for in vitro and in vivo deliveryBioMedCentral Biotechnology 3:2.
Dätwyler, D.A., Magyar, J.P., Weikert, C., Wightman, L., Wagner, E., Eppenberger, H.M.
(2003)
Reactivation of the mitosis-promoting factor in postmitotic cardiomyocytesCell Tissues Organs 175, 61-71.
Düchler M., Pengg M., Schüller S., Pfneisl F., Bugingo Chr., Brem G., Wagner E., Schellander K., Müller M.
(2001)
Somatic Gene Transfer into the Lactating Ovine Mammary GlandJ. Gene Medicine 4, 282-291.
Wolschek, M.F., Thallinger, C., Kursa, M., Rössler, V., Allen, M., Lichtenberger, C., Kircheis, R., Lucas, T., Willheim, M., Reinisch, W., Gangl, A., Wagner, E., Jansen, B.
(2001)
Specific systemic non-viral gene delivery to human hepatocellular carcinoma xenografts in SCID miceHepatology 36, 1106-1114.
Düchler, M., Pengg, M., Brunner, S., Müller, M., Brem, G., Wagner, E.
(2001)
Transfection of epithelial cells is enhanced by combined treatment with mannitol and polyethyleneglycolJ. Gene Medicine 3, 115-124.
van Slooten, M.L., Hayon, I., Babai, I., Zakay-Rones, Z., Wagner, E., Storm, G., Kedar, E.
(2001)
Immunoadjuvant activity of interferon-gamma-liposomes co-administered with influenza vaccinesBiochim. Biophys. Acta 1531, 99-110.
Kircheis, R., Blessing, T., Wightman, L., Brunner, S., Wagner, E.
(2001)
Tumor targeting with surface-shielded ligand-polycation DNA complexesJ. Controlled Rel. 72, 165-170.
Kircheis, R., Wightman, L., Wagner, E.
(2001)
Design and gene delivery activity of modified polyethyleniminesAdv. Drug Del. Rev. 53, 341-358
Blessing, T., Kursa, M., Holzhauser, R., Kircheis, R., Wagner, E.
(2001)
Different Strategies for Formation of PEGylated EGF-conjugated PEI/DNA Complexes for Targeted Gene DeliveryBioconjug. Chem. 12, 529-537.
Wightman, L., Kircheis, R., Rössler, V., Carotta, S., Ruzicka, R., Kursa, M., Wagner, E.
(2001)
Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivoJ. Gene Medicine 3, 362-372.
Felzmann, T., Buchberger, M., Lehner, M., Printz, D., Kircheis, R., Wagner, E., Gadner, H., Holter, W.
(2001)
Functional maturation of dendritic cells by exposure to CD40L transgenic tumor cells or primary fibroblasts and keratinocytesCancer Letters 168, 145-154.
Ogris, M., Steinlein, P., Carotta, S., Brunner , S., Wagner E.
(2001)
article 21.,
Kircheis, R., Wightman, L., Kursa, M., Smrekar, B., Ostermann, E., Wagner, E.
(2001)
Surface-shielded polycation-based systems targeting reporter and therapeutic genes to distant tumorsGene Ther. Mol. Biol. 6, 159-167.
Kircheis, R., Wagner, E.
(2000)
Polycation/DNA complexes for in vivo gene deliveryGene Therapy and Regulation 1, 95-114.
Brunner, S., Sauer, T., Carotta, S., Cotten, M., Saltik, M., Wagner, E.
(2000)
Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirusGene Therapy 7, 401-407.
Huber, M., Limat, A., Wagner, E., Hohl, D.
(2000)
Efficient in vitro transfection of human keratinocytes with an adenovirus-enhanced receptor-mediated systemJ. Invest. Dermatol. 114, 661-666.
Kircheis, R., Küpcü, Z., Wallner, G., Rössler, V., Schweighoffer, T., Wagner, E.
(2000)
IL-2 gene-modified allogeneic melanoma cell vaccines can induce cross-protection against syngeneic tumor challenge in miceCancer Gene Therapy 7, 870-878.
Felzmann, T., Buchberger, M., Jechlinger, M., Kircheis, R., Wagner, E., Gadner, H.
(2000)
Xenogenization by tetanus toxoid loading into lymphoblastoid cell lines and primary human tumor cells mediated by polycations and liposomesCancer Letters 161, 241-250.
Book Chapters / Volumes
Dohmen, C., Ogris, M.
(2009)
Receptor-Mediated Delivery of Proteins and Peptides to Tumors.
In ‘Pharmaceutical Perspectives of Cancer Therapeutics.’ Mahato, RI and Lu, Y (Eds), Springer Science + Business Media, New York, in press
Ogris, M., Wagner, E.
(2008)
Linear Polyethylenimine: Synthesis and transfection procedures for in vitro and in vivo.
In: ‘Gene Transfer: Delivery and Expression of DNA and RNA, A Laboratory Manual.’ Friedmann, T and Rossi, J (Eds), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, pp 521-526
Bonsted, A., Wagner, E., Prasmickaite, L., Høgset, A., Berg, K.
(2008)
Photochemical enhancement of DNA delivery by EGF receptor targeted polyplexes.
In: “Methods in Molecular Biology, vol. 434: Volume 2“, J. M. LeDoux (Ed.), Humana Press, pp. 171-181.
Philipp, A., Wagner, E.
(2008)
Receptor-targeted polyplexes for DNA and siRNA delivery.
In: "Gene and Cell Therapy. Therapeutic Mechanisms and Strategies”, 3rd Edition, N. SmythTempleton (Ed), CRC Press, pp. 341-361
Wagner, E.
(2007)
Gentherapie.
In: "Pathophysiologie, Molekulare, zelluläre, systemische Grundlagen von Krankheiten”. S. Schwarz, O. Förster, M. Peterlik, K. Schauenstein, G. Wick (Eds.), Maudrich, Vienna, pp. 3-1 - 3-8
Wagner, E., Ogris, M.
(2007)
Strategies to incorporate CPPs into synthetic viruses for tumor-targeted gene therapy. Chapter 26 in ?Cell-Penetrating Peptides, 2nd Edition, Ü. Langel (Ed.), CRC Press, pp. 455-468.
Wagner, E.
(2007)
Selective Targeting to Tumors and Other Tissues with Cell-Penetrating Peptides: In Vivo Applications.
In 'Cell-Penetrating Peptides, 2nd Edition, Ü. Langel (Ed.), CRC Press, pp. 409-411.
Wagner, E.
(2007)
Nonviral gene transfer to tumors. A new route to programmed drug delivery?.
In: 'Eurocancer 2007', M. Boiron, M. Marty (Eds), John Libbey Eurotext, Paris, pp 115-116.
Wagner, E., Klöckner, J.
(2006)
Gene delivery using polymer therapeutics.
Chapter in 'Polymer Therapeutics: Polymers as Drugs, Conjugates and Gene Delivery Systems”, R. Duncan, R. Satchi-Fainaro (Eds.), Springer-Verlag, p. 135-173.
Fahrmeir, J., Ogris, M.
(2006)
Transferrin receptor mediated delivery of protein and peptide drugs into tumors.
Chapter in ‘Delivery of Protein and Peptide Drugs in Cancer ‘, V. Torchillin (Ed), World Scientific Publishing, p. 206-223.
Ameri, K., Wagner, E.
(2005)
Receptor-Targeted Polyplexes.
Chapter in 'Gene Therapy. Therapeutic Mechanisms and Strategies', 2 nd Edition , N. Smyth-Templeton ( Ed ), Marcel Dekker Inc , New York.
Wagner, E., Klöckner, J.
(2005)
Gene delivery using polymer therapeutics.
Chapter in 'Polymer Therapeutics: Polymers as Drugs , Conjugates and Gene Delivery Systems', Ruth Duncan , Ronit Satchi-Fainaro ( Eds. ).
Wagner, E., Klöckner, J., Ogris, M.
(2005)
Optimizing polyplexes into synthetic viruses for tumor-targeted gene therapy.
Chapter in 'Non-viral Gene Therapy: Gene Design and Delivery', K. Taira , K. Kataoka , T. Niidome ( Eds. ), Springer-Verlag Tokyo , p. 237-245.
Wagner, E., Culmsee, C., Boeckle, S.
(2005)
Targeting of Polyplexes: Towards Synthetic Virus Vector Systems.
Chapter 13 in 'Non-Viral Vectors for Gene Therapy , Second Edition', L. Huang , M.C. Hung , E. Wagner ( Eds. ), Elsevier Academic Press , Advances in Genetics 53, 333-354.
Walker, G. F., Wagner, E.
(2004)
Nonviral vector systems for cancer gene therapy.
Chapter 24 in 'Cancer Gene Therapy', D.T. Curiel and J.T. Douglas ( Eds ), Humana Press , Totowa , New Jersey , p. 367-378.
Kircheis, R., Wagner, E.
(2004)
Transferrin Receptor-Targeted Gene Delivery Systems.
Chapter 34 in 'Polymeric Gene Delivery , Principles and Applications', M.M. Amiji ( Ed ), CRC Press , Boca Raton , London , New York , Washington D.C. , p. 537-556.
Ogris, M., von Gersdorff, K., van der Piepen, S., Brunner, S., Wagner, E.
(2004)
Non-viral gene delivery systems - delivery techniques and therapeutic concepts for cancer.
Chapter 7 in 'Advanced Biomaterials for Medical Applications', D. W. Thomas ( Ed ), Kluwer Academic Publishers , p. 79-92.
Ogris, M.
(2004)
Polyethylenimine and Copolymers..
Chapter in 'Polymeric Gene Delivery: Principles and Application', Mansoor M. Amiji (Ed), CRC Press, Boca Raton (FL), p. 97-106.
Wightman, L., Kircheis, R., Wagner, E.
(2003)
Polymer-Based Gene Delivery Systems.
Chapter 5 in 'Pharmaceutical Gene Delivery Systems', Drugs and the Pharmaceutical Sciences Vol. 131, A. Rolland , S. M. Sullivan ( Eds. ), Marcel Dekker Inc. , USA , p. 109-135.
Boeckle, S., Wagner, E., Ogris, M.
(2002)
Transmembrane Targeting of DNA with Membrane Active Peptides.
Chapter 23 in 'Biomedical Aspects of Drug Targeting', V. R. Muzykantov , V. P. Torchilin ( Eds ), Kluwer Academic Publishers , Boston / Dordrecht / London , p. 441-458.
Ameri, K., Wagner, E.
(2000)
Receptor mediated gene transfer.
In 'Gene Therapy: Therapeutic Mechanisms and Strategies', N. Smyth-Templeton , D. Lasic ( Eds ), Marcel Dekker Inc. , pp141-164.
Kircheis, R., Kursa, M., Wightman, L., Brunner, S., Ogris, M., Schüller, S., Wagner, E.
(2000)
Systemic in vivo gene delivery into tumors by the use of transferrin-polyethylenimine DNA complexes.
NATO Science Series, A: Life Sciences, 323, pp186-191.
Kircheis, R., Wightman, L., Ogris, M., Brunner, S., Kursa, M., Schüller, S., Wagner, E.
(2000)
Receptor -mediated gene transfer based on plasmid DNA complexes.
Chapter in: Progress in Gene Therapy: Basic and Clinical Frontiers, Bertolotti, Parvez, Nagatsu Eds., VSP BV, pp183-203.
G. Storm, Wagner, E.
(1999)
Volume 38 in Adv1.
Drug Del. Rev. Theme title: Membrane destabilization for improved cytosolic delivery.
L. Huang, M.C. Hung, Wagner, E.
(1999)
Nonviral Vectors for Gene Therapy, Academic Press, San Diego..
Wagner, E.
(1999)
Gentherapie.
In: Pathophysiologie, Wick, et al (Eds), Gustav-Fischer-Verlag, Stuttgart.
Wagner, E.
(1999)
Ligand-polycation conjugates for receptor-targeted gene transfer.
Chapter 10 (p. 208-227) in 'Non-Viral Vectors for Gene Therapy', L. Huang, M.C. Hung, E. Wagner (Eds), Academic Press.
Cotten, M., Wagner, E.
(1998)
Receptor-mediated gene delivery strategies1.
The Development of Human Gene Therapy, CSHL Press, p. 261-277.
Wagner, E.
(1998)
Polylysine-conjugate based DNA delivery. pp. 309-322.
In: Self-assembling complexes for gene delivery. From laboratory to clinical trials, Kabanov, Felgner, Seymour (Eds), Wiley, England.
Wagner, E.
(1998)
Receptor-mediated gene transfer.
In: Gene Therapy, Principles and applications, Blankenstein (Ed), Birkhäuser, Basel, Switzerland.
van Slooten, M.L., Koppenhagen, F.J., Bergers, J.J., Kircheis, R., Crommelin, D.J.A., wagner_e, Storm, G.
(1997)
Liposomal delivery of cytokines for anticancer vacination.
In 'Future Strategies for Drug Delivery with Particulate Systems', JE Diederichs and RH Müller (Eds), CRC Press.
