Chemical Synthesis and Natural Product Chemistry

A substantial part of our research program is dedicated to chemical synthesis and natural product chemistry. We are convinced that the vast majority of natural products have not yet been found and that a wealth of interesting chemistry and biology awaits discovery. As synthetic organic chemists, we are intrigued by the structural beauty and functional sophistication of these molecules. Through total synthesis, we gain insight into their mechanism of action and biosynthetic origin. In addition, the total synthesis of complex natural products provides an ideal platform for the invention or discovery of new synthetic methodology or the validation of modern reactions in a challenging environment.

More thoughts on the future of natural product synthesis can be found here: "Finding Function and Form". Also, check out our list of completed synthetic targets. And test your retrosynthetic skills and synthetic knowledge with our Denksport!