The Trauner Research Group
Chemical synthesis & neuroscience
Publications
136. "Studies toward the Biomimetic Total Synthesis of (-)-PF-1018" Webster, R.; Gaspar, B.; Mayer, P.; Trauner, D. Org. Lett. 2013, 15, 1866-1869. [PDF]
135. "Optical Control of Metabotropic Glutamate Receptors" Levitz, J.; Pantoja, C.; Gaub, B; Janovjak, H.; Reiner, A.; Hoagland, A.; Schoppik, D.; Kane, B.; Stawski, P.; Schier, A. F.; Trauner, D.*; Isacoff, E. Y.* Nat. Neurosci. 2013, 16, 507-516. [PDF]
134. "Optical Control of Neurotransmission" Izquierdo-Serra, M.; Trauner, D.; Lobet, A.; Gorostiza, P. Biophys. J. 2013, 104, 497a.
133. “Characterization of a Diffusible Signaling Factor from Xylella Fastidiosa” Beaulieu, E. D.; Ionescu, M.; Chaterjee, S.; Yokota, K.; Trauner, D.; Lindow, S. mBio 2013, 4, e00539-12. [PDF]
132. "Optical Modulation of Neurotransmission Using Calcium Photocurrents Through the Ion Channel LiGluR" Izquierdo-Serra, M.; Trauner, D.; Lobet, A.; Gorostiza, P. Frontiers. Mol. Neurosci. 2013, 6, doi: 10.3389/fnmol.2013.00003, [PDF]
131. "Mode of Cell Death Induction by Pharmacological Vacuolar H+-ATPase (V-ATPase) Inhibition" Von Schwarzenberg, K.; Wiedmann, R. M.; Zahler, S.; Trauner, D.; Vollmar, A. M. J. Biol. Chem. 2013, 288, 1385-1396. [PDF]
130. "The V-ATPase-inhibitor Archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1" Wiedmann, R. M.; von Schwarzenberg, K.; Palamidessi, A.; Schreiner, L.; Kubisch, R.; Liebl, J.; Schempp, C.; Trauner, D.; Vereb, G.; Zahler, S.; Wagner, E. ; Muller, R. ; Scita, G.; Vollmar, A. M. Cancer Res. 2012, 72, 5976-5987. [PDF]
129. "Label-Free Microscale Thermophoresis Discriminates Sites and Affinity of Protein–Ligand Binding" Seidel, S. A.; Wienken, C. J.; Geissler, S.; Jerabek-Willemsen, M.; Duhr, S.; Reiter, A.; Trauner, D.; Braun, D.; Baaske, P. Angew. Chem. Int. Ed. 2012, 51, 10656-10659. [PDF] CeNS Publication Award 2012. [PDF]
128. "The crystal structure of the Dess–Martin periodinane" Schröckeneder, A. ; Stichnoth, D.; Mayer, P.; Trauner, D. Beilstein J. Org. Chem. 2012, 8, 1523–1527. [PDF]
127. "Azo-Propofols: Photochromic Potentiators of GABAA Receptors" Stein, M.; Middendorp, S. J.; Carta, V.; Pejo, E.; Raines, D. E.; Forman, S. A.; Sigel, E.; Trauner, D. Angew. Chem. Int. Ed. 2012, 51, 10500–10504. [PDF] Highlighted in C&EN 2012, 90, Issue 39, p. 30. [PDF] [Video]
126. "Evolution of a Synthetic Strategy for the Variecolortides" Kuttruff, C. A.; Mayer, P.; Trauner, D. Eur. J. Org. Chem. 2012, 27, 5151-5161. [PDF]
125. "Photochemical Restoration of Visual Responses in Blind Mice" Polosukhina, A.; Litt, J.; Tochitsky, I.; Nemargut, J.; Sychev, Y.; De Kouchkovsky, I.; Huang, T.; Borges, K.; Trauner, D.; Van Gelder, R. N.; Kramer R. H. Neuron 2012, 75, 271-282. [PDF] Highlighted in Nature 2012, Vol 488, p. 8. [PDF] Highlighted in C&EN 2012, 90, Issue 31, p. 12. [PDF]
124. "Exploring the Pharmacology and Action Spectra of Photochromic Open-Channel Blockers" Fehrentz, T.; Kuttruff, C. A.; Huber, F. M. E.; Kienzler M. A.; Mayer P.; Trauner, D. ChemBioChem 2012, 13, 1746-1749. [PDF]
123. "A Unified Approach to trans-Hydrindane Sesterterpenoids" Hog, D. T., Mayer, P., Trauner, D. J. Org. Chem. 2012, 77, 5838-5843. [PDF]
122. "Synthetic Approaches Toward Sesterterpenoids" Hog, D. T.; Webster, R.; Trauner, D. Nat. Prod. Rep. 2012, 29, 752-779. [PDF]
121. "Stereoselective Total Syntheses of Herbicidin C and Aureonuclemycin through Late-Stage Glycosylation" Hager, D.; Mayer, P.; Paulitz, C.; Tiebes, J.; Trauner, D. Angew. Chem. Int. Ed. 2012, 51, 6525–6528. [PDF]
120. "A Total Synthesis Prompts the Structure Revision of Haouamine B" Matveenko, M.; Liang, G.; Lauterwasser, E. M. W.; Zubia, E.*; Trauner, D.* J. Am. Chem. Soc. 2012, 134, 9291–9295. [PDF]
119. "A Photochromic Agonist of AMPA Receptors" Stawski, P.; Sumser, M.; Trauner, D. Angew. Chem. Int. Ed. 2012, 51, 5748-5751. [PDF]
118. "Total Synthesis of Exiguamines A and B Inspired by Catecholamine Chemistry" Sofiyev, V.; Lumb, J.-P. ; Volgraf, M.; Trauner, D. Chem. Eur. J. 2012, 18, 4999-5005. [PDF]
117. "Rapid Optical Control of Nociception with an Ion Channel Photoswitch" Mourot, A.; Fehrentz, T.; Bautista, D.; Trauner, D.*; Kramer, R.* Nature Methods 2012, 9, 396-402. [PDF]
116. "An Approach to Aminonaphthoquinone Ansamycins Using a Modified Danishefsky Diene" Kuttruff, C. A.; Geiger, S.; Cakmak, M.; Mayer, P.; Trauner, D. Org. Lett. 2012, 14, 1070-1073. [PDF]
115. "Optical Control of Genetically Engineered Nicotinic Acetyl Choline Receptors" Tochitsky, I.; Banghart M. R.; Mourot, A.; Zhao, J.Z.; Gaub, B.; Kramer, R.; Trauner, D., Nature Chemistry 2012, 4, 105-111. [PDF]
114. "Optochemical Genetics" Fehrentz, T.; Schönberger, M.; Trauner, D.; Angew. Chem. Int. Ed. 2011, 50, 12156-12182. [PDF]
113. "LiGluR Restores Visual Responses in Rodent Models of Inherited Blindness" Caporale, N.; Kolstad, K. D.; Lee, T.; Tochitsky, I.; Dalkara, D.; Trauner, D.; Kramer, R.; Dan, Y.; Isacoff E. Y.; Flannery, J. G. Molecular Therapy 2011, 19, 1212–1219. [PDF] Commentary [PDF]
112. "Tuning Photochromic Ion Channel Blockers" Mourot, A.; Kienzler, M. A.; Banghart, M. R.; Fehrentz, T.; Huber, F. M. E.; Stein, M.; Kramer, R. H.; Trauner, D. ACS Chemical Neuroscience 2011, 2, 536–543. [PDF]
111. “An efficient synthesis of loline alkaloids" Cakmak, M.; Mayer, P.; Trauner, D Nat. Chem. 2011, 3, 543-545. [PDF]
110. “Optogenetic photochemical control of designer K+ channels in mammalian neurons" Doris L. Fortin, D. L.; Dunn, T. W.; Fedorchak, A; Allen, D.; Montpetit, R.; Banghart, M. R.; Trauner, D.; Adelman, J. P.; Kramer, R. H. J. Neurophys. 2011, 106, 488-496.
109. “Synthetic Studies toward A-74528“ Hager, A.; Mazunin, D.; Mayer, P.; Trauner, D. Org. Lett. 2011, 13, 1386–1389. [PDF]
108. “Crocipodin, a benzotropolone pigment from from the mushroom Leccinum crocipodium (Boletales)“ Kerschensteiner, L.; Loebermann, F.; Steglich, W.; Trauner, D. Tetrahedron 2011, 67, 1536-1539. [PDF]
107. “Concise Total Synthesis of Variecolortide A and B Through an Unusual Hetero Diels-Alder Reaction“ Kuttruff, C. A.; Zipse, H.; Trauner, D. Angew. Chem. Int. Ed. 2011 50, 1402-1405. [PDF]
106. “Toward the Total Synthesis of Maoecrystal V: Establishment of Contiguous Quaternary Stereocenters“ Baitinger, I. ; Mayer, P.; Trauner, D. Org. Lett. 2010, 12, 5656-5659. [PDF]
105. “Theoretical Investigation of the Rubicordifolin Cascade“ Lumb, J.-P.; Krinsky, J.; Trauner, D. Org. Lett. 2010, 22, 5162-5165. [PDF]
104. “Structural basis of open channel block in a prokaryotic pentameric ligand-gated ion channel“ Hilf, R. J. C.; Bertozzi, C.; Zimmermann, I.; Reiter, A.; Trauner, D.; Dutzler, R. Nature Struct. Mol. Biol. 2010, 17, 1330-1337. [PDF]
103. “Pharmacology of ionotropic glutamate receptors: A structural perspective.“ Stawski P., Janovjak H., Trauner D. Bioorg Med Chem. 2010, 18, 7759-7772. [PDF]
102. “A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing“ Janovjak, H.; Szobota, S.; Wyart, C.; Trauner, D.; Isacoff, E. Y. Nature Neurosci. 2010, 13, 1027–1032. [PDF]
101. “A signal processing analysis of Purkinje cells in vitro“ Abrams, Z. R.; Warrier, A.; Trauner, D.; Zhang, X. Frontiers in Neural Circuits 2010, 4, 1–13. [PDF]
100. “Biomimetic Synthesis of (–)-Pycnanthuquinone C via Vinyl Quinone Diels-Alder Reaction“ Löbermann, F.; Mayer, P.; Trauner, D. Angew. Chem. Int. Ed. 2010, 49, 6199–6202.
99. “Total Synthesis of Newbouldine via Reductive N-N Bond Formation“ Pangerl, M.; Chambers C. H.; Trauner, D. Tetrahedron 2010, 66, 6626-6631. [PDF]
98. “On the Development of Catalytic Carba-6π Electrocyclizations“ Bishop, L. M.; Roberson, R. E.; Bergman, R. G.; Trauner, D. Synthesis 2010, 13, 2233–2244.
97. “Total Synthesis of Coralloidolides A, B, C, and E“ Kimbrough, T. J.; Roethle, P. A.; Mayer, P.; Trauner, D. Angew. Chem. Int. Ed. 2010, 49, 2619-2621. [PDF]
96. “Photochromic Blockers of Voltage-Gated Potassium Channels“ Banghart, M. R.; Mourot, A.; Fortin, D. L.; Yao, J. Z.; Kramer, R. H.; Trauner, D. Angew. Chem. Int. Ed. 2009, 48, 9097-9101. [PDF]
95. “New photochemical tools for controlling neuronal activity“ Kramer, R. H.; Fortin, D. L.; Trauner, D. Curr Opin Neurobiol 2009, 19, 1-9. [PDF]
94. “Optogenetic dissection of a behavioural module in the vertebrate spinal cord“ Wyart C.; Del Bene, F.; Warp, E.; Scott, E. K.; Trauner, D.; Baier, H.; Isacoff E. Y. Nature 2009, 461, 407-410. [PDF] [Movie]
93. “Calix[4]arene-based conical-shaped ligands for voltage-dependent potassium channels “ Martos, V.; Bell, S. C.; Santos, E.; Isacoff, E. Y.; Trauner, D., de Mendoza, J. PNAS 2009, 106, 10482-10486. [PDF]
92. “Nanosculpting reversed wavelength sensitivity into a photoswitchable iGluR“ Numano, R.; Szobota, S.; Laud, A. Y.; Gorostiza, P.; Volgraf, M.; Roux, B.; Trauner, D.; Isacoff, E. Y. PNAS 2009, 106, 6814-6819. [PDF]
91. “Total Synthesis of (±)-Rhazinal Using Novel Palladium-Catalyzed Cyclizations“ Bowie, A. L. Jr.; Trauner D. J Org Chem 2009, 74, 1581-1586. [PDF]
90. "Catalysis of 6π Electrocyclizations" Bishop, L.M.; Barbarow, J. E.; Bergman, R.G.; Trauner, D. Angew. Chem. Int. Ed. 2008, 47, 8100-8103. [PDF]
89. "Biomimetic synthesis of the IDO inhibitors exiguamine A and B" Volgraf, M.; Lumb, J.P.; Brastianos, H. C.; Carr, G.; Chung, M. K. W.; Munzel, M.; Mauk, A. G.; Andersen, R. J.; Trauner, D. Nature Chem. Bio. 2008, 4, 535-537. [PDF]
88. "ortho-Quinone Methides from para-Quinones: Total Synthesis of Rubioncolin B." Lumb, J.P.; Choong, K. C.; Trauner, D. J. Am. Chem. Soc. 2008, 130, 9230-9231. [PDF]
87. "Vinyl Quinones as Diels-Alder Dienes: Concise Synthesis of (-)-Halenaquinone." Kienzler, M. A.; Suseno, S; Trauner, D. J. Am. Chem. Soc. 2008, 130, 8604-8605. [PDF]
86. "Introduction: Chemical Approaches to Neurobiology" (guest editorial). Trauner, D. Chem. Rev. 2008, 105, 1499. [PDF]
85. "Mechanistic Investigations into the Acid-Catalyzed Cyclization of a Vinyl Ortho-Quinone Methide." Bishop, L.M.; Houk, K.N.; Winkler, M.; Bergman, R.G.; Trauner, D. Chem. Eur. J. 2008, 14, 5405-5408. [PDF]
84. "A Structural Link between Inactivation and Block of a K+ Channel." Ader, C.; Schneider, R.; Hornig, S.; Velisetty, P.; Wilson; E. M.; Lange, A.; Giller, K.; Ohmert, I.; Martin-Eauclaire, M.-F.; Trauner, D.; Becker, S.; Pongs, O.; Baldus, M. Nature Struct. Mol. Biol. 2008, 15, 605. [PDF]
83. "The Chemistry of Marine Furanocembranoids, Pseudopteranes, Gersolanes, and Related Natural Products." Roethle, P. A.; Trauner D. Nat. Prod. Rep. 2008, 25, 298. [PDF]
82. "Photochemical Control of Endogenous Ion Channels and Cellular Excitability". Fortin, D.L.; Banghart, M.R., Dunn, T.D.; Borges, K.; Wagnaar, D.A.; Gaudry, Q.; Karakossian, M.; Otis, T.W.; Kristan, W.B.; Trauner, D.: Kramer, R.H. Nature Meth. 2008, 5, 331. [PDF]
81. "Conjugate Addition of Allyl Stannanes with Concomitant Triflation." Beaulieu, E. D.; Voss, L.; Trauner, D. Org. Lett. 2008, 10, 869. [PDF]
80. "Biomimetic Synthesis of the Shimalactones." Sofiyev, V.; Navarro, G.; Trauner, D. Org. Lett. 2008, 10, 149. [PDF]
79. "Regulating Enzymatic Activity with a Photoswitchable Affinity Label." Harvey, J.; Trauner, D. Chem. Biochem. 2008, 9, 191. [PDF]
78. „Enolates“ Trauner, D. in „Science of Synthesis, Houben-Weyl, Methods of Molecular Transformations“ Volume 32, pp. 547-588, Stuttgart, New York: Thieme 2008.
77. „Enols“ Trauner, D. in „Science of Synthesis, Houben-Weyl, Methods of Molecular Transformations“ Volume 32, pp. 533-545, Stuttgart, New York: Thieme 2008.
76. "All Optical Interface for Parallel, Remote, and Spatiotemporal Control of Neuronal Activity." Wang, S.; Szobota, S.; Wang, Y.; Volgraf, M.; Liu, Z.; Sun, C.; Trauner, D.; Isacoff, E. Y.; Zhang, X. Nano Lett. 2007, 7, 3859. [PDF]
75. "Reversible Photomechanical Switching of Individual Engineered Molecules at a Metallic Surface." Comstock, M. J.; Levy, N.; Kirakosian, A.;Cho, J.; Lauterwasser, F.; Harvey, J. H.; Strubbe, D. A.;Fréchet, J. M. J.; Trauner, D.; Louie, S. G.; Crommie, M. F. Phys. Rev. Lett. 2007, 99, 038301. [PDF]
74. "Total Synthesis of (-)-Archazolid B." Roethle, P. A.; Chen, I. T.; Trauner, D. J. Am. Chem. Soc. 2007, 129, 8960. [PDF]
73. "Mechanisms of photoswitch conjugation and light activation of an ionotropic glutamate receptor." Gorostiza, P.; Volgraf, M.; Numano,R.; Szobota, S.; Trauner, D.; Isacoff, E. Y.Proc. Natl. Acad. Sci. 2007, 104, 10865. [PDF]
72. "Total Synthesis of Smenochromene B Through Ring Contraction." Rosa, C.P.; Kienzler, M.; Olson, B.S.; Liang, G.; Trauner, D. Tetrahedron 2007, 63, 6529. [PDF]
71. "Remote Control of Neuronal Activity With a Light-Gated Glutamate Receptor." Szobota, S.; Gorostiza, P.; Del Bene, F.; Wyart, C.; Fortin, D. L.; Kolstad, K. D.; Tulyathan, O.; Volgraf, M.; Numano, R.; Aaron, H. L.; Scott, E. K.; Kramer, R. H.; Flannery, J.; Baier, H.; Trauner, D.; Isacoff, E. Neuron 2007, 54, 535. [PDF]
70. "Functionalized Azobenzenes Through Cross-Coupling with Organotrifluoroborates" Harvey, J. H.; Bulter, B. K.; Trauner, D. Tetrahedron Lett. 2007, 48, 1661. [PDF]
69. "Concise Synthesis of the Bacterial DNA Primase Inhibitor (+)-Sch 642305" Wilson, E. M.; Trauner, D. Org. Lett. 2007, 9, 1327. [PDF]
68. "Reversibly Caged Glutamate: A Photochromic Agonist of Ionotropic Glutamate Receptors" Volgraf, M.; Gorostiza, P.; Szobota,S.; Helix, M. R.; Isacoff, E. Y.; Trauner, D. J. Am. Chem. Soc. 2007, 129, 260. [PDF]
67. "The Meirwein-Eschenmoser-Claisen Rearrangement." Gradl, S. N.; Trauner, D. In Claisen Rearrangements, Hiersemann, M.; Nubbemeyer, U., Eds; Weinheim: Wiley-VCH 2005, Chapter 7. [PDF]
66. "Total Synthesis of (-)-Heptemerone B and (-)-Guanacastepene E" Miller, A. K.; Hughes, C. C.; Kennedy-Smith, J. J.; Gradl, S. N.; Trauner, D. J. Am. Chem. Soc. 2006, 128, 17057. [PDF]
65. "Engineering Light-Gated Ion Channels" Banghart, M. R.; Volgraf, M.; Trauner, D. Biochemistry 2006, 45, 15129. [PDF]
64. "Exploring Biosynthetic Relationships among Furanocembranoids: Synthesis of (-)-Bipinnatin J, (+)-Intricarene, (+)-Rubifolide, and (+)-Isoepilophodione B " Roethle, P. A.; Hernandez, P. T.; Trauner, D. Org. Lett. 2006, 8, 5901. [PDF]
63. "Development of a Friedel-Crafts Triflation" Grundl, M. A.; Kaster, A.; Beaulieu, E. D.; Trauner, D. Org. Lett. 2006, 8, 5429. [PDF]
62. "Photochemical Origin of the Immunosuppressive SNF4435C/D and Formation of Orinocin through Polyene Splicing" Müller, M.; Kusebauch, B.; Liang, G.; Beaudry, C. M.; Trauner, D.; Hertweck, C. Angew. Chem. Int. Ed. 2006, 46, 7835. [PDF]
61. "Mapping the Chemistry of Highly Unsaturated Pyrone Polyketides" Miller, A.K.; Trauner, D. Synlett. 2006, 14, 2295. [PDF]
60. "Light-Induced Depolarization of Neurons Using a Modified Shaker K Channel and a Molecular Photoswitch" Chambers, J. J.; Banghart, M. R.; Trauner, D.; Kramer, R. H. J. Neurophysiol. 2006, 96 2792. [PDF]
59. "Synthesis of Taiwaniaquinoids via Nazarov Triflation" Liang, G.; Xu, Y.; Seiple, I.B.; Trauner, D. J. Am. Chem. Soc. 2006, 128, 11022. [PDF]
58. "Expedient Synthesis of (±)-Bipinnatin J." Roethle, P. A.; Trauner, D. Org. Lett. 2006, 8, 345. [PDF]
57. "Synthetic Studies Toward the Haouamines." Grundl, M. A.; Trauner, D. Org. Lett. 2006, 8, 23. [PDF]
56. "Allosteric Control of an Ionotropic Glutamate Receptor with an Optical Switch." Volgraf, M.; Gorostiza, P.; Numano, R.; Kramer, R. H.; Isacoff, E.; Trauner, D. Nature Chem. Bio. 2006, 1, 47. [PDF]. Featured in "Science": [PDF].
55. "Pericyclic Reactions of Prenylated Naphthoquinones: Biomimetic Synthesis of Mollugin and Microphyllaquinone." Lumb, J. P.; Trauner, D. Org. Lett. 2005, 7, 5865. [PDF]
54. "Photochemical Tools for Remote-Control of Ion Channels in Excitable Cells." Kramer, R. H.; Chambers, J. J.; Trauner, D. Nature Chem. Bio. 2005, 1, 360. [PDF]
53. "Biosynthetic and Biomimetic Electrocyclizations." Beaudry, C. M.; Malerich, J. P.; Trauner, D. Chem. Rev. 2005, 105, 4757. [PDF]
52. "Concise Synthesis of (±)-Rhazinilam through Direct Coupling." Bowie, A. L., Jr.; Hughes, C. C.; Trauner, D. Org. Lett. 2005, 7, 5207. [PDF]
51. "Photosensitized Conversion of 9,10-Deoxytridachione to Photodeoxytridachione." Zuidema, D. R.; Miller, A. K.; Trauner, D.; Jones, P. B. Org. Lett. 2005, 7, 4959. [PDF]
50. "Total Synthesis of (-)-SNF4435 C and (+)-SNF4435 D." Beaudry, C. M.; Trauner, D. Org. Lett. 2005, 7, 4475. [PDF]
49. "A Glimpse at the Grail." Trauner, D. Nature Chem. Bio. 2005, 1, 189. [PDF]
48. "Infrared Hole Burning and Conformational Change in a Borane-Ammonia Complex." Endicott, C. A.; Strauss, H. L.; Hughes, C. C.; Trauner, D. J. Phys Chem. A 2005, 109, 7714. [PDF]
47. "An Electrochemical Approach to the Guanacastepenes." Hughes, C. C.; Miller, A. K.; Trauner, D. Org. Lett. 2005, 7, 3425. [PDF]
46. "Mining the Tetraene Manifold: Total Synthesis of Complex Pyrones from Placobranchus ocellatus." Miller, A. K.; Trauner, D. Angew. Chem., Int. Ed. 2005, 44, 4602. [PDF]
45. "Biomimetic Synthesis of Elysiapyrones A and B." Barbarow, J. E.; Miller, A. K.; Trauner, D. Org. Lett. 2005, 7, 2901. [PDF]
44. "Stereoselective Syntheses of the Bioactive Polypropionates Aureothin, N-Acetylaureothamine, and Aureonitrile." Liang, G.; Seiple, I. B.; Trauner, D. Org. Lett. 2005, 7, 2837. [PDF]
43. "Rational Design of a Chiral Palladium(0) Olefin Complex of Unprecedented Stability." Grundl, M. A.; Kennedy-Smith, J. J.; Trauner, D. Organometallics 2005, 24, 2831. [PDF]
42. "Biomimetic Synthesis of Antimalarial Naphthoquinones." Malerich, J. P.; Maimone, T. J.; Elliott, G. I.; Trauner, D. J. Am. Chem. Soc. 2005, 127, 6276. [PDF]. Correction [PDF]
41. "Dienophile Twisting Causes Rate Enhancements in Intramolecular Diels-Alder Cycloadditions: A DFT Study." Khuong, K. S.; Beaudry, C.; Trauner, D.; Houk, K. N. J. Am. Chem. Soc. 2005, 127, 3688. [PDF]
40. "Biomimetic Synthesis and Structure Elucidation of Rubicordifolin, a Cytotoxic Natural Product from Rubia cordifolia." Lumb, J. P.; Trauner, D. J. Am. Chem. Soc. 2005, 127, 2870. [PDF]
39. "Stereoselective Synthesis of the Placidenes and Cyercene A." Liang, G.; Miller, A. K.; Trauner, D. Org. Lett. 2005, 7, 819. [PDF]
38. "Concise Synthesis of (±)-Smenochromene D (Likonide B)." Olson, B. S.; Trauner D Synlett 2005, 700. [PDF]
37. "Biomimetic Synthesis of Natural Products Isolated from Bignoniaceae." Malerich, J. P.; Trauner, D. In Strategies and Tactics in Organic Synthesis; Harmata, M., Ed.; Elsevier: Amsterdam, 2004; Vol. 5. pp 417-436. [PDF]
36. "Light-Activated Ion Channels for Remote Control of Neuronal Firing." Banghart, M. R.; Borges, K.; Isacoff, E. Y.; Trauner, D.; Kramer R. H. Nature Neuroscience 2004, 7, 1381. [PDF]. Featured in "Science": [PDF].
35. "Palladium-Catalyzed Couplings to Nucleophilic Heteroarenes: The Total Synthesis of (-)-Frondosin B." Hughes, C. C.; Trauner, D. Tetrahedron 2004, 60, 9675. [PDF]
34. "Enantioselective Nazarov Reactions through Catalytic Asymmetric Proton Transfer." Liang, G.; Trauner, D. J. Am. Chem. Soc. 2004, 126, 9544. [PDF]
33. "The Total Synthesis of (-)-Crispatene." Miller, A. K.; Byun, D. H.; Beaudry, C. M.; Trauner, D. Proc. Natl. Acad. Sci. 2004, 101, 12019. [PDF]
32. "Metabolic Modulation of Potassium Channels." Trauner, D.; Kramer, R. H. Science STKE 2004, 233, pe20. [PDF]
31. "Efficient Nazarov Cyclizations of 2-Alkoxy-1,4-pentadien-3-ones." Liang, G.; Gradl, S. N.; Trauner, D. Org. Lett. 2003, 5, 4931. [PDF]
30. "Potassium Channels: Symmetric, Selective, Sensitive." Trauner, D. Angew. Chem., Int. Ed. 2003, 42, 5671. [PDF]
29. "Direct Catalytic Asymmetric Amination of Aldehydes: Synthesis of Evans Oxazolidinones and α-Amino Acids." Hughes, C. C.; Trauner, D. Chemtracts 2003, 16, 511. [PDF]
28. "Development of Novel Lewis Acid Catalyzed Cycloisomerizations: Synthesis of Bicyclo[3.1.0]hexenes and Cyclopentenones." Miller, A. K.; Banghart, M. R.; Beaudry, C. M.; Suh, J. M.; Trauner, D. Tetrahedron 2003, 59, 8919. [PDF]
27. "Synthetic Studies toward the Guanacastepenes." Hughes, C. C.; Kennedy-Smith, J. J.; Trauner, D. Org. Lett. 2003, 5, 4113. [PDF]
26. "Protein Surface Recognition by Rational Design: Nanomolar Ligands for Potassium Channels." Gradl, S.; Felix, J. P.; Isacoff, E. Y.; Garcia, M. L.; Trauner, D. J. Am. Chem. Soc. 2003, 125, 12668. [PDF]
25. "Reductive Cyclization of β-Hydroxy Nitriles: A New Synthesis of Glycoxylamines." Dorsey, A. D.; Barbarow, J. E.; Trauner, D. Org. Lett. 2003, 5, 3237. [PDF]
24. "Biomimetic Synthesis of (±)-Pinnatal and (±)-Sterekunthal A." Malerich, J. P.; Trauner, D. J. Am. Chem. Soc. 2003, 125, 9554. [PDF]
23. "Intramolecular Diels-Alder Reactions of 5-Vinyl-1,3-Cyclohexadienes." Ng, S. M.; Beaudry, C. M.; Trauner, D. Org. Lett. 2003, 5, 1701. [PDF]
22. "Total Synthesis of (±)-Photodeoxytridachione through a Lewis Acid Catalyzed Cyclization." Miller, A. K.; Trauner, D. Angew. Chem., Int. Ed. 2003, 42, 549. [PDF]
21. "Enzymatic Desymmetrization of a Centrosymmetric Diacetate." Böhm, C.; Austin, W. F.; Trauner, D. Tetrahedron: Asymmetry 2003, 14, 71. [PDF]
20. "The Total Synthesis of (-)-Amathaspiramide F." Hughes, C. C.; Trauner, D. Angew. Chem., Int. Ed. 2002, 41, 4556. [PDF]
19. "Boron-Ammonia Complexes Stabilized by Hydrogen Bonding." Hughes, C. C.; Scharn, D.; Mulzer, J.; Trauner, D. Org. Lett. 2002, 4, 4109. [PDF]
18. "Synthetic Studies Toward SNF4435 C and SNF4435 D." Beaudry, C. M.; Trauner, D. Org. Lett. 2002, 4, 2221. [PDF]
17. "Concise Total Synthesis of (-)-Frondosin B Using a Novel Palladium Catalyzed Cyclization." Hughes, C. C.; Trauner, D. Angew. Chem., Int. Ed. 2002, 41, 1569. [PDF]. Correction [PDF]
16. "A Practical Variant of the Claisen-Eschenmoser Rearrangement: Synthesis of Unsaturated Morpholine Amides." Gradl, S. N.; Kennedy-Smith, J. J.; Kim, J.; Trauner, D. Synlett 2002, 3, 411. [PDF]
From doctoral and postdoctoral studies:
15. "The B-Alkyl Suzuki-Miyaura Cross-Coupling Reaction: Development, Mechanistic Study and Applications in Natural Product Synthesis." Chemler, S. R.; Trauner, D.; Danishefsky, S. J. Angew. Chem., Int. Ed. 2001, 40, 4544. [PDF]
14. "Concise Stereoselective Routes to Advanced Intermediates Related to Natural and Unnatural Pinnaic Acid." Carson, M. W.; Kim, G.; Hentemann, M. F.; Trauner, D.; Danishefsky, S. J. Angew. Chem., Int. Ed. 2001, 40, 4450. [PDF] Correction [PDF]
13. "On the Conformations of Halichlorine and the Pinnaic Acids: Nitrogen Inversion as a Possible Determinant of Biological Profile." Trauner, D.; Danishefsky, S. J. Helv. Chim. Acta 2000, 83, 2344. [PDF]
12. "Synthesis of Immunomodulatory Marine Natural Products." Danishefsky, S. J.; Inoue, M.; Trauner, D. in "The Role of Natural Products in Drug Discovery," Ernst Schering Research Foundation (ESRF) Workshop 32, pp. 1-24, Heidelberg, New York: Springer 2000.
11. "Morphine Synthesis and Biosynthesis - an Update." Novak, B. H.; Hudlicky, T.; Reed, J. W.; Mulzer, J.; Trauner, D. Curr. Org. Chem. 2000, 4, 343. [PDF]
10. "Total Synthesis of (+)-Halichlorine, an Inhibitor of VCAM-1 Expression." Trauner, D.; Schwarz, J. B.; Danishefsky, S. J. Angew. Chem., Int. Ed. 1999, 38, 3542. [PDF]
9. "Studies Toward the Total Synthesis of Halichlorine: Asymmetric Synthesis of the Spiroqinolizidine Subunit." Trauner, D.; Danishefsky, S. J. Tetrahedron Lett. 1999, 40, 6513.
8. "Insight into the Mechanism of the Saegusa Oxidation: Isolation of a Novel Palladium(0) Tetraolefin Complex." Porth, S.; Bats, J. W.; Trauner, D.; Giester, G.; Mulzer, J. Angew. Chem., Int. Ed. 1999, 38, 2015. [PDF]
7. "Practical Synthesis of (-)-Morphine." Mulzer, J.; Trauner, D. Chirality 1999, 11, 475.
6. "About the Use of Molecular Workbenches and Platforms in Organic Synthesis." Mulzer, J., Schein, K.; Bohm, I.; Trauner, D. Pure Appl. Chem. 1998, 70, 1487.
5. "Synthesis of Enantiomerically Pure Morphine Alkaloids: The Hydrophenathrene Route." Trauner, D.; Bats, J. W.; Werner, A.; Mulzer, J. J. Org. Chem. 1998, 63, 5908.
4. "New Ventures in the Construction of Complex Heterocycles: Synthesis of Morphine and Hasubanan Alkaloids." Trauner, D.; Porth, S.; Opatz, T.; Bats, J. W.; Giester, G.; Mulzer, J. Synthesis 1998, 653.
3. "The Phenanthrenone Approach to Opium Alkaloids: Formal Total Synthesis of Morphine by Sigmatropic Rearrangement." Mulzer, J.; Bats, J. W.; List, B.; Opatz, T.; Trauner, D. Synlett 1997, 5, 441.
2. "Formal Total Synthesis of (-)-Morphine by Cuprate Conjugate Addition." Mulzer, J.; Duerner, G.; Trauner, D. Angew. Chem., Int. Ed. 1997, 35, 2830. [PDF]
1. "Stereoselective Insertion of Ketenes into O,O-Acetals: Synthesis of β-Alkoxy Esters and 1,4-Dioxepanones." Mulzer, J.; Trauner, D.; Bats, J. W. Angew. Chem., Int. Ed. 1996, 35, 1970. [PDF]