@ Ludwig-Maximilians-Universität München (Germany)
@ Philipps-Universität Marburg (Germany)
@ ETH Zürich (Switzerland)
@ MIT (Cambridge, USA)
@ Max-Planck-Institut for Medical Research (Heidelberg, Germany)
at Other publications and activity

Citations follow PubMed listings
Ludwig-Maximilians-Universität München (Germany):
219 C. Ebert, N. Simon, S. Schneider T. Carell
ChemBioChem 2017, doi:10.1002/cbic.201700169
Structural insights into the recognition of N2-aryl- and C8-aryl DNA lesions by the repair protein XPA/Rad14.
218 S. Schiffers, C. Ebert, R. Rahimoff, O. Kosmatchev, J. Steinbacher, A.-V. Bohne, F. Spada, S. Michalakis, M. Müller, T. Carell
Angew. Chem. Int. Ed. 2017, doi:10.1002/anie.201700424
Quantitative LC–MS Provides No Evidence for m6dA or m4dC in the Genome of Mouse Embryonic Stem Cells and Tissues.
217 A. S. Schröder, E. Parsa, K. Iwan, F. R. Traube, M. Wallner, S. Serdjukow, T. Carell
Chem. Commun. 2016, doi:10.1039/C6CC07517G
2´-(R)-Fluorinated mC, hmC, fC and caC triphosphates are substrates for DNA polymerases and TET-enzymes.
216 L. Heidinger, A. Kneuttinger, G. Kazshiwazaki, S. Weber, T. Carell, E. Schleicher
FEBS Lett. 2016, doi:10.1002/1873-3468.12498
Direct Observation of a Deoxyadenosyl Radical in an Active Enzyme Environment.
215 A. Dallmann, A. Beribisky, F. Gnerlich, M. Rübbelke, S. Schiesser, T. Carell, M. Sattler
Chem. Eur. J. 2016, 22 (43), 15350-15359 doi:10.1002/chem.201602784
Site-Specific Isotope-Labeling of Inosine Phosphoramidites and NMR Analysis of an Inosine-Containing RNA Duplex.
214 M. Su, A. Kirchner, S. Stazzoni, M. Müller, M. Wagner, A. S. Schröder, T. Carell
Angew. Chem. Int. Ed. 2016, 55 (39), 11797-11800 doi:10.1002/anie.201605994
5-Formylcytosine could be a Semipermanent Base in Specific Genome Sites.
213 A. S. Schröder, O. Kotljarova, E. Parsa, K. Iwan, N. Raddaoui, T. Carell
Org. Lett. 2016, 18 (17), 4368-4371 doi:10.1021/acs.orglett.6b02110
Synthesis of (R)-Configured 2´-Fluorinated mC, hmC, fC, and caC Phosphoramidites and Oligonucleotides.
212 B. Thienpont, J. Steinbacher, H. Zhao, F. D'Anna, A. Kuchnio, A. Ploumakis, B. Ghesquière, L. Van Dyck, B. Boeckx, L. Schoonjans, E. Hermans, F. Amant, V. N. Kristensen, K. P. Koh, M. Mazzone, M. L. Coleman, T. Carell, P. Carmeliet, D. Lambrechts
Nature, 2016, 537, 63-68 doi:10.1038/nature19081
Tumour hypoxia causes DNA hypermethylation by reducing TET activity.
211 C. M. Greco, P. Kunderfranco, M. Rubino, V. Larcher, P. Carullo, A. Anselmo, K. Kurz, T. Carell, A. Angius, M. V. G. Latronico, R. Papait, G. Condorelli
Nature Comm. 2016, 7, 12418 doi:10.1038/ncomms12418
DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy.
210 N. Simon, C. Ebert, S. Schneider
Chem. Eur. J. 2016, 22 (31), 10782-10785 doi:10.1002/chem.201602438
Structural Basis for Bulky-Adduct DNA-Lesion Recognition by the Nucleotide Excision Repair Protein Rad14.
209 S. Becker, I. Thoma, A. Deutsch, T. Gehrke, P. Mayer, H. Zipse, T. Carell
Science, 2016, 352 (6287), 833-836 doi:10.1126/science.aad2808
A high-yielding, strictly regioselective prebiotic purine nucleoside formation pathway.
208 S. C. Koch, N. Simon, C. Ebert, T. Carell
Quaterly Reviews of Biophysics, 2016, 49, e5 doi:10.1017/S0033583515000268
Molecular mechanisms of xeroderma pigmentosum (XP) proteins.
207 O. Bogdanovic, A. H. Smits, E. de la Calle Mustienes, J. J. Tena, E. Ford, R. Williams, U. Senanayake, M. D. Schultz, S. Hontelez, I. van Kruijsbergen, T. Rayon, F. Gnerlich, T. Carell, G. J. C. Veenstra, M. Manzanares, T. Sauka-Spengler, J. R. Ecker, M. Vermeulen, J. L. Gómez-Skarmeta, R. Lister
Nature Genetics, 2016, 48, 417-426 doi:10.1038/ng.3522
Active DNA demethylation at enhancers during the vertebrate phylotypic period.
206 L. Klier, E. Aranzamendi, D. Ziegler, J. Nickel, K. Karaghiosoff, T. Carell, P. Knochel
Org. Lett. 2016, 18(5), 1068-1071 doi:10.1021/acs.orglett.6b00190
Lewis Acid Triggered Regioselective Magnesiation and Zincation of Uracils, Uridines, and Cytidines.
205 S. Datz, C. Argyo, M. J. Gattner, V. Weiss, K. Brunner, J. Bretzler, C. von Schirnding, A. A. Torrano, F. Spada, M. Varbel, H. Engelke, C. Bräuchle, T. Carell, T. Bein
Nanoscale, 2016, 8, 8101-8110 doi:10.1039/C5NR08163G
Genetically designed biomolecular capping system for mesoporous silica nanoparticles enables receptor-mediated cell uptake and controlled drug release.
204 D. B. Bucher, C. L. Kufner, A. S. Schulter, T. Carell, W. Zinth
J. Am. Chem. Soc. 2016, 138 (1), 186-190 doi:10.1021/jacs.5b09753
UV-Induced Charge Transfer States in DNA Promote Sequence Selective Self-Repair.
203 N. C. Gassen, G. R. Fries , A. S. Zannas , J. Hartmann , J. Zschocke , K. Hafner , T. Carrillo-Roa , J. Steinbacher , S. N. Preißinger , L. Hoeijmakers , M. Knop , F. Weber , S. Kloiber , S. Lucae , G.P. Chrousos , T. Carell , M. Ising , E. B. Binder , M. V. Schmidt , J. Rüegg , T. Rein
Science Signal. 2015, 8 (404), ra119, doi:10.1126/scisignal.aac7695
Chaperoning epigenetics: FKBP51 decreases the activity of DNMT1 and mediates epigenetic effects of the antidepressant paroxetine.
202 D. B. Bucher, B. M. Pilles, T. Carell, W. Zinth
J. Phys. Chem. B, 2015, 119 (28), 8685-8692
Dewar Lesion Formation in Single- and Double-Stranded DNA is Quenched by Neighboring Bases.
201 M. Wagner, J. Steinbacher, T. F. Kraus, S. Michalakis, B. Hackner, T. Pfaffeneder, A. Perera, M. Müller, A. Giese, H. A. Kretzschmar, T. Carell
Angew. Chem. Int. Ed. 2015, 54 (42), 12511-12514 doi:10.1002/anie.201502722
Age-Dependent Levels of 5-Methyl-, 5-Hydroxymethyl-, and 5-Formylcytosine in Human and Mouse Brain Tissues.
200 L. Schuster, L. Rothmund, X. He, Kirsten L. V. Landuyt, H. Schweikl, E. Hellwig, T. Carell, R. Hickel, F.-X. Reichl, C. Högg
Dent. Mater. 2015, 31, 6, 745-757
Effect of Opalescence® bleaching gels on the elution of dental composite components.
199 S. C. Koch, J. Kuper, K. L. Gasteiger, N. Simon, R. Strasser, D. Eisen, S. Geiger, S. Schneider, C. Kisker, T. Carell
PNAS, 2015, doi:10.1073/pnas.1508509112
Structural insights into the recognition of cisplatin and AAF-dG lesion by Rad14 (XPA)
198 L. Rothmund, M. Shehata, K. L. Van Landuyt, H. Schweikl, T. Carell, W. Geurtsen, E. Hellwig, R. Hickel, F.-X. Reichl, C. Högg
Dent. Mater. 2015, 31, 6, 496-504 doi:10.1016/
Release and protein binding of components from resin based composites in native saliva and other extraction media
197 S. Schiesser, B. Hackner, M. Vrabel, W. Beck, T. Carell
Eur. J. Org. Chem. 2015, 2654-2660
Synthesis and DNA-Damaging Properties of Cisplatin-N-Mustard Conjugates
196 M Ehrlich, M. J. Gattner, B. Viverge, J. Bretzler, D. Eisen, M. Stadlmeier, M. Vrabel, T. Carell
Chem. Eur. J. 2015, 21, 1-5
Orchestrating the Biosynthesis of an Unnatural Pyrrolysine Amino Acid for Its Direct Incorporation into Proteins Inside Living Cells
195 A. Perera, D. Eisen, M. Wagner, S. K. Laube, A. F. Künzel, S. Koch, J. Steinbacher, E. Schulze, V. Splith, N. Mittermeier, M. Müller, M. Biel, T. Carell, S. Michalakis
Cell Rep. 2015, 11, 1-12
TET3 Is Recruited by REST for Context-Specific Hydroxymethylation and Induction of Gene Expression
194 L. Penter, B. Maier, U. Frede, B. Hackner, T. Carell, C. Hagemeier, M. Truss
Target Oncol. 2015, doi:10.1007/s11523-014-0354-5
A rapid screening system evaluates novel inhibitors of DNA methylation and suggests F-box proteins as potential therapeutic targets for high-risk neuroblastoma
193 M. Su, M. Tomas–Gamasa, T. Carell
Chem. Sci. 2015, 6, 632-638
DNA based multi-copper ions assembly using combined pyrazole and salen ligandosides
192 K. Brunner, J. Harder, T. Halbach, J. Willibald, F. Spada, F. Gnerlich, K. Sparrer, A. Beil, L. Möckl, C. Bräuchle, K-K Conzelmann, T. Carell
Angew. Chem. Int. Ed. 2014, 53, 1-5
Cell-Penetrating and Neurotargeting Dendritic siRNA Nanostructures
191 M. Tomas–Gamasa, S. Serdjukow, M. Su, M. Müller, T. Carell
Angew. Chem. Int. Ed. 2014, 54, 796-800
"Post-It" Type Connected DNA Created with a Reversible Covalent Cross-Link
190 O. Ziv, A. Zeisel, N. Mirlas-Neisberg, U. Swain, R. Nevo, N. Ben-Chetrit, M. Paola Martelli, R. Rossi, S.n Schiesser, C. E. Canman, T. Carell, N. E. Geacintov, B. Falini, E. Domany, Z. Livneh
Nature Comm. 2014, 5:5437
Identification of novel DNA-damage tolerance genes reveals regulation of translesion DNA synthesis by nucleophosmin.
189 A. Benjdia, K. Heil, A. Winkler, T. Carell, I. Schlichting.
Chem. Commun. 2014, 50, 14201-14204
Rescuing DNA repair activity by rewiring the H-atom transfer pathway in the radical SAM enzyme, spore photoproduct lyase
188 D. B. Bucher, A. Schlueter, T. Carell, W. Zinth
Angew. Chem. Int. Ed. 2014, 53, 11366-11369
Watson-Crick Base Pairing Controls Excited-State Decay in Natural DNA
187 A. Biela, F. Coste, F. Culard, M. Guerin, S. Goffinont, K. Gasteiger, J. Cieśla, A. Winczura, Z. Kazimierczuk, D. Gasparutto, T. Carell, B. Tudek, B. Castaing
Nucleic Acids Res. 2014, 42, 10748-10761
Zinc finger oxidation of Fpg/Nei DNA glycosylases by 2-thioxanthine: biochemical and X-ray structural characterization
186 K. Sadeghian, D. Flaig, I. D. Blank, S. Schneider, R. Strasser, D. Stathis, M. Winnacker, T. Carell, C. Ochsenfeld
Angew. Chem. Int. Ed. 2014, 53, 10044-10048
Ribose-Protonated DNA Base Excision Repair: A Combined Theoretical and Experimental Study
185 L. I. Kroeze, M. G. Aslanyan, A. van Rooij, T. N. Koorenhof-Scheele, M. Massop, T. Carell, J. B. Boezeman, J.-P. Marie, C. J. M. Halkes, T. de Witte, G. Huls, S. Suciu, R. A. Wevers, B. A. van der Reijden, J. H. Jansen
Blood 2014, 124, 1110-1118
Characterization of acute myeloid leukemia based on levels of global hydroxymethylation
184 T. Pfaffeneder, F. Spada, M. Wagner, C. Brandmayr, S. K. Laube, D. Eisen, M. Truss, J. Steinbacher, B. Hackner, O. Kotljarova, D. Schuermann, S. Michalakis, O. Kosmatchev, S. Schiesser, B. Steigenberger, N. Raddaoui, G. Kashiwazaki, U. Müller, C. G. Spruijt, M. Vermeulen, H. Leonhardt, P. Schär, M. Müller & T. Carell
Nature Chem. Biol. 2014, 10, 574-581
Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA
183 N. Kitsera, K. Gasteiger, B. Lühnsdorf, J. Allgayer, B. Epe, T. Carell, A. Khobta
PLOS One 2014, 9 (4), e94405
Cockayne Syndrome: Varied Requirement of Transcription-Coupled Nucleotide Excision Repair for the Removal of Three Structurally Different Adducts from Transcribed DNA
182 S. Serdjukow, F. Kink, B. Steigenberger, M. Tomas–Gamasa, T. Carell
Chem. Commun. 2014, 50, 1861-1863
Synthesis of γ-labeled nucleoside 5'-triphosphates using click chemistry
181 D.B. Bucher, B.M. Pilles, T. Carell, W. Zinth
Proc. Natl. Acad. Sci. USA, 2014, 111 (12), 4369-4374
Charge separation and charge delocalization identified in long-living states of photoexcited DNA
180 P. Bashtrykov, A. Rajavelu, B. Hackner, S. Ragozin, T. Carell, A. Jeltsch
ChemBioChem, 2014, 15, 743-8
Targeted Mutagenesis Results in an Activation of DNA Methyltransferase 1 and Confirms an Autoinhibitory Role of its RFTS Domain
179 D.B. Bucher, B.M. Pilles, T. Pfaffeneder, T. Carell, W. Zinth
Chemphyschem, 2014, 15, 420-3
Fingerprinting DNA oxidation processes: IR characterization of the 5-methyl-2´-deoxycytidine radical cation
178 C.N. Buechner, K. Heil, G. Michels, T. Carell, C. Kisker, I. Tessmer
J. Biol. Chem. 2014, 289, 3613-3624
Strand specific recognition of DNA damages by XPD provides insights into Nucleotide Excision Repair substrate versatility
177 M. Su, M. Tomás-Gamasa, S. Serdjukow, P. Mayer, T. Carell
Chem. Commun. (Camb.) 2014, 50, 409-411
Synthesis and properties of a Cu(II) complexing pyrazole ligandoside in DNA
176 A.S. Schröder, J. Steinbacher, B. Steigenberger, F.A. Gnerlich, S. Schiesser, T. Pfaffeneder, T. Carell
Angew. Chem. Int. Ed. 2014, 53, 315-8 (selected as Hot-Paper)
Synthesis of a DNA Promoter Segment Containing All Four Epigenetic Nucleosides: 5-Methyl-, 5-Hydroxymethyl-, 5-Formyl-, and 5-Carboxy-2’-Deoxycytidine
175 A.C. Kneuttinger, G. Kashiwazaki, S. Prill, K. Heil, M. Müller, T. Carell
Photochem. Photobiol. 2014, 90, 1-14
Formation and Direct Repair of UV-induced Dimeric DNA Pyrimidine Lesions
174 I. Thoma, T. Carell
Eur. J. Org. Chem. 2013, 21, 4483-85
Total Synthesis of the Hypermodified tRNA Nucleoside Epoxyqueuosine
173 M. Vrabel, P. Kölle, K.M. Brunner, M.J. Gattner, V. López-Carillo, R. de Vivie-Riedle, T. Carell
Chemistry, 2013, 19, 13309-12
Norbornenes in Inverse Electron-Demand Diels-Alder Reactions
172 S. Schneider, M.J. Gattner, M. Vrabel, V. Flügel, V. López-Carillo, S. Prill, T. Carell
Chembiochem, 2013, 14, 2114-8
Structural Insights into Incorporation of Norbornene Amino Acids for Click Modification of Proteins
171 S. Schiesser, T. Pfaffeneder, K. Sadeghian, B. Hackner, B. Steigenberger, A.S. Schröder, J. Steinbacher, G. Kashiwazaki, G. Höfner, K.T. Wanner, C. Ochsenfeld, T. Carell
J. Am. Chem. Soc. 2013, 135, 14593-9
Deamination, Oxidation and C-C bond Cleavage Reactivity of 5-Hydroxymethylcytosine, 5-Formylcytosine and 5-Carboxycytosine
170 M. Shehata, J. Durner, A. Eldenez, K. Van Landuyt, P. Styllou, L. Rothmund, R. Hickel, H. Scherthan, W. Geurtsen, B. Kaina, T. Carell, F.X. Reichl
Dent. Mater. 2013, 29, 971-9
Cytotoxicity and induction of DNA double-strand breaks by components leached from dental composites in primary human gingival fibroblasts
169 K. Groll, S.M. Manolikakes, X.M. du Jourdin, M. Jaric, A. Bredihhin, K. Karaghiosoff, T. Carell, P. Knochel
Angew. Chem. Int. Ed. 2013, 52, 6776-80
Regioselective Metalations of Pyrimidines and Pyrazines by Using Frustrated Lewis Pairs of BF3-OEt2 and Hindered Magnesium- and Zinc-Amide Bases
168 T.H. Gehrke, U. Lischke, K.L. Gasteiger, S. Schneider, S. Arnold, H.C. Müller, D.S. Stephenson, H. Zipse T. Carell
Nature Chem. Biol. 2013, 9, 455-61
Unexpected non-Hoogsteen-based mutagenicity mechanism of FaPy-DNA lesions
167 C.G. Spruijt, F. Gnerlich, A.H. Smits, T. Pfaffeneder, P.W.T.C. Jansen, C. Bauer, M. Münzel, M. Wagner, M. Müller, F. Khan, H.C. Eberl, A. Mensinga, A.B. Brinkman, K. Lephikov, U. Müller, J. Walter, R. Boelens, H. van Ingen, H. Leonhardt, T. Carell, M. Vermeulen
Cell, 2013, 152, 1146-59.
Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives
166 A. Hienzsch, C. Deiml, V. Reiter, T. Carell
Chemistry, 2013, 19, 4244-8.
Total Synthesis of the Hypermodified RNA Bases Wybutosine and Hydroxywybutosine and Their Quantification Together with Other Modified RNA Bases in Plant Materials
165 B. Steigenberger, S. Schiesser, B. Hackner, C. Brandmayr, S.K. Laube, J. Steinbacher, T. Pfaffeneder, T. Carell
Org. Lett. 2013, 15, 366-369.
Synthesis of 5-Hydroxymethyl-, 5-Formyl-, and 5-Carboxycytidine-triphosphates and Their Incorporation into Oligonucleotides by Polymerase Chain Reaction
164 M. Ehrlich, T. Carell
Eur. J. Org. Chem. 2013, 1, 77-83.
Total Syntheses and Biological Evaluation of 3-O-Methylfunicone and Its Derivatives Prepared by TMPZnCl·LiCl-Mediated Halogenation and Carbonylative Stille Cross-Coupling
163 A.C. Kneuttinger, K. Heil, G. Kashiwazaki, T. Carell
Chem. Commun. (Camb.) 2013, 49, 722-724
The Radical SAM Enzyme Spore Photoproduct Lyase Employs a Tyrosyl Radical for DNA Repair
162 M.J. Gattner, M. Vrabel, T. Carell
Chem. Commun. (Camb.) 2013, 49, 379-381
Synthesis of ε-N-propionyl-, ε-N-butyryl-, and ε-N-crotonyl-lysine containing histone H3 using the pyrrolysine system
161 C. Brandmayr, M. Wagner, T. Brückl, D. Globisch, D. Pearson, A.C. Kneuttinger, V. Reiter, A. Hienzsch, S. Koch, I. Thoma, P. Thumbs, S. Michalakis, M. Müller, M. Biel, T. Carell
Angew. Chem. Int. Ed. 2012, 51, 11162-5.
Isotope-Based Analysis of Modified tRNA Nucleosides Correlates Modification Density with Translational Efficiency
160 T.F. Kraus, D. Globisch, M. Wagner, S. Eigenbrod, D. Widmann, M. Münzel, M. Müller, T. Pfaffeneder, B. Hackner, W. Feiden, U. Schüller, T. Carell, H.A. Kretzschmar
Int. J. Cancer. 2012, 131, 1577-90.
Low values of 5-hydroxymethylcytosine (5hmC), the "sixth base" are associated with anaplasia in human brain tumors
159 J. Willibald, J. Harder, K. Sparrer, K.-K. Conzelmann, T. Carell
J. Am. Chem. Soc. 2012, 134, 12330-3.
Click Modified Anandamide siRNA Enables Delivery and Gene Silencing in Neuronal and Immune Cells
158 J. Timper, K. Gutsmiedl, C. Wirges, J. Broda, M. Noyong, J. Mayer, T. Carell, U. Simon
Angew. Chem. Int. Ed. 2012, 51, 7586-8.
Surface "Click" Reaction of DNA followed by Directed Metalization for the Construction of Contactable Conducting Nanostructures
157 T. Carell, C. Brandmayr, A. Hienzsch, M. Müller, D. Pearson, V. Reiter, I. Thoma, P. Thumbs, M. Wagner,
Angew. Chemie. Int. Ed. 2012, 51, 7110-7131.
Structure and Function of Noncanonical Nucleobases
156 A. Benjdia, K. Heil, T. R. Barends, T. Carell, I. Schlichting
Nucleic Acids Res. 2012, 40, 9308-18
Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzyme
155 V. Reiter, D. M. S. Matschkal, M. Wagner, D. Globisch, A. C. Kneuttinger, M. Müller, T. Carell
Nucleic Acids Res. 2012, 40, 6235-6240.
The CDK5 repressor CDK5RAP1 is a methylthiotransferase acting on nuclear and mitochondrial RNA
154 S. Schiesser, P. Mayer, T. Carell, W. Beck
Z. Naturforsch. 2012, 67b, 849-852.
Molecular and Crystal Structure of Potassium-l-alaninato-dichloridoplatinate(II), K[Pt(l-alaO)Cl2]
153 S. Schiesser, B. Hackner, T. Pfaffeneder, M. Müller, C. Hagemeier, M. Truss, T. Carell
Angew. Chemie. Int. Ed. 2012, 51, 6516-6520.
Mechanism and Stem-Cell Activity of 5-Carboxycytosine Decarboxylation Determined by Isotope Tracing
152 B.P. Fingerhut, S. Oesterling, K. Haiser, K. Heil, A. Glas, W.J. Schreier, W. Zinth, T. Carell, R. de Vivie-Riedle
J. Chem. Phys. 2012, 136, 204307.
ONIOM approach for non-adiabatic on-the-fly molecular dynamics demonstrated for the backbone controlled dewar valence isomerization
151 E. Kaya, M. Vrabel, C. Deiml, S. Prill, V. S. Fluxa, T. Carell
Angew. Chem. Int. Ed. 2012, 51, 4466-9.
A Genetically encoded Norbornene Amino Acid for the Mild and Selective Modification of Proteins in a Copper-free Click Reaction
150 C. Walmacq, A.C. Cheung, M.L. Kireeva, L. Lubkowska, C. Ye, D. Gotte, J. N. Strathern, T. Carell, P. Cramer, M. Kashlev
Mol. Cell. 2012, 46, 18-29.
Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage
149 D. Stathis, U. Lischke, S. C. Koch, C. A. Deiml, T. Carell
J. Am. Chem. Soc. 2012, 134, 4925-30.
Discovery and Mutagenicity of a Guanidinoformimine Lesion as a new Intermediate of the Oxidative Deoxyguanosine Degradation Pathway
148 K. Haiser, B. P. Fingerhut, K. Heil, A. Glas, T. T. Herzog, B. M. Pilles, W. J. Schreier, W. Zinth, R. de Vivie-Riedle, T. Carell
Angew. Chem. Int. Ed. 2012, 51, 408-11.
Mechanism of UV-Induced Formation of Dewar Lesions in DNA
147 N. Diamant, A. Hendel, I. Vered, T. Carell, T. Reissner, N. de Wind, N. Geacinov, Z. Livneh
Nucleic Acids Res. 2012, 40, 170-80.
DNA damage bypass operates in the S and G2 phases of the cell cycle and exhibits differential mutagenicity
146 M. Münzel, U. Lischke, D. Stathis, T. Pfaffeneder, F. A. Gnerlich, C. A. Deiml, S. C. Koch, K. Karaghiosoff, T. Carell
Chemistry, 2011, 17, 13782-13788.
Selected as News Item in "Chemistry Views" on 22 November 2011
Improved Synthesis and Mutagenicity of Oligonucleotides Containing 5-Hydroxymethylcytosine, 5-Formylcytosine and 5-Carboxylcytosine
145 F. Civril, M. Bennett, M. Moldt, T. Deimling, G. Witte, S. Schiesser, T. Carell, K. P. Hopfner
EMBO Rep. 2011, 12, 1127-34.
The RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signalling
144 D. Globisch, D. Pearson, A. Hienzsch, T. Brückl, M. Wagner, I. Thoma, P. Thumbs, V. Reiter, A. Kneuttinger, M. Müller, S. Sieber, T. Carell
Angew. Chem. Int. Ed. 2011, 50, 9739-9742.
Systems-Based Analysis of Modified tRNA Bases
143 J. Fei, N. Kaczmarek, A. Luch, A. Glas, T. Carell, H. Naegeli
PLoS Biol. 2011, 9, e1001183.
Regulation of Nucleotide Excision Repair by UV-DDB: Prioritization of Damage Recognition to Internucleosomal DNA
142 S. Kiontke, Y. Geisselbrecht, R. Pokorny, T. Carell, A. Batschauer, L. O. Essen
EMBO J. 2011, 30, 4437-49.
Crystal structures of an archaeal class II DNA photolyase and its complex with UV-damaged duplex DNA
141 A. Hendel, P. H. Krijger, N. Diamant, Z. Goren, P. Langerak, J. Kim, T. Reissner, K. Y. Lee, N. E. Geacintov, T. Carell K. Myung, S. Tateishi, A. D’Andrea, H. Jacobs, Z. Livneh
PLoS Genet. 2011, 7, e1002262.
PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells
140 C. Kaul, M. Müller, M. Wagner, S. Schneider, T. Carell
Nature Chem. 2011, 3, 794-800.
Reversible bond formation enables replication and amplification of a crosslinking salen complex as an orthogonal base pair
139 M. Vrabel, E. Kaya, S. Prill, V. Ehmke, T. Carell
Collect. Czech. Chem. Commun. 2011, 76, 1089-1101.
Optimization of the posttranslational click modification of proteins
138 K. Heil, A. C. Kneuttinger, S. Schneider, U. Lischke, T. Carell
Chemistry, 2011, 17, 9651-7.
Crystal Structures and Repair Studies Reveal the Identity and the Base-Pairing Properties of the UV-Induced Spore Photoproduct DNA Lesion
137 A. Stadler, J. O. Delos Santos, E. S. Stensrud, A. Dembska, G. L. Silva, S. Liu, N. I. Shank, E. Kunttas-Tatli, C. J. Sobers, P. M. E. Gramlich, T. Carell, L. A. Peteanu, B. M. McCartney, B. A. Armitage
Bioconjug. Chem. 2011, 22, 1491-502.
Fluorescent DNA Nanotags Featuring Covalently Attached Intercalating Dyes: Synthesis, Antibody Conjugation, and Intracellular Imaging
136 K. Heil, D. Pearson, T. Carell
Chem. Soc. Rev. 2011, 40, 4271-8.
Chemical investigation of light induced DNA bipyrimidine damage and repair
135 Y. V. Le Bihan, M. Angeles Izquierdo, F. Coste, P. Aller, F. Culard, T. H. Gehrke, K. Essalhi, T. Carell, B. Castaing
Nucleic Acids Res. 2011, 39, 6277-90.
5-Hydroxy-5-methylhydantoin DNA lesion, a molecular trap for DNA glycosylases
134 N. Kitsera, D. Stathis, B. Lühnsdorf, H. Müller, T. Carell, B. Epe, A. Khobta
Nucleic Acids Res. 2011, 39, 5926-34.
8-Oxo-7,8-dihydroguanine in DNA does not constitute a barrier to transcription, but is converted into transcription-blocking damage by OGG1
133 T. Pfaffeneder, B. Hackner, M. Truss, M. Münzel, M. Müller, C. A. Deiml, C. Hagemeier, T. Carell
Angew. Chem. Int. Ed. 2011, 50, 7008-12.
The discovery of 5-formylcytosine in embryonic stem cell DNA
132 M. Münzel, D. Globisch, T. Carell
Angew. Chem. Int. Ed. 2011, 50, 6460-8.
5-Hydroxymethylcytosine, the sixth base of the genome
131 D. Pearson, T. Carell
Nucleic Acids Res. 2011, 39, 4818-26.
Assay of both activities of the bifunctional tRNA-modifying enzyme MnmC reveals a kinetic basis for selective full modification of cmnm5s2U to mnm5s2U
130 D. Pearson, A. Hienzsch, M. Wagner, D. Globisch, V. Reiter, D. Özden, T. Carell
Chem. Commun. (Camb.) 2011, 47, 5196-8.
LC-MS based quantification of 2′-ribosylated nucleosides Ar(p) and Gr(p) in tRNA
129 M. Münzel, C. Szeibert, A. F. Glas, D. Globisch, T. Carell
J. Am. Chem. Soc. 2011, 133, 5186-9.
Discovery and synthesis of new UV-induced intrastrand C(4-8)G and G(8-4)C photolesions
128 M. Wenninger, D. Fazio, U. Megerle, C. Trindler, S. Schiesser, E. Riedle, T. Carell
Chembiochem, 2011, 12, 703-6.
Flavin-induced DNA photooxidation and charge movement probed by ultrafast transient absorption spectroscopy
127 S. Zimdars, X. Mollat du Jourdin, F. Crestey, T. Carell, P. Knochel
Org. Lett. 2011, 13, 792-795.
Trifunctionalization of the Purine Scaffold Using Mg and Zn Organometallic Intermediates
126 D. Fazio, C. Trindler, K. Heil, C. Chatgilialoglu, T. Carell
Chemistry, 2011, 17, 206-212.
Investigation of Excess-Electron Transfer in DNA Double-Duplex Systems Allows Estimation of Absolute Excess-Electron Transfer and CPD Cleavage Rates
125 D. Globisch, M. Münzel, M. Müller, S. Michalakis, M. Wagner, S. Koch, T. Brückl, M. Biel, T. Carell
PLoS One, 2010, 5, e15367.
Tissue Distribution of 5-Hydroxymethylcytosine and Search for Active Demethylation Intermediates
124 M. Münzel, D. Globisch, C. Trindler, T. Carell
Org. Lett. 2010, 12, 5671-5673.
Efficient Synthesis of 5-Hydroxymethylcytosine Containing DNA
123 S. Schorr, T. Carell
Chembiochem, 2010, 11, 2534-2537.
Mechanism of Acetylaminofluorene-dG Induced Frameshifting by Polymerase η
122 S. Schorr, S. Schneider, K. Lammens, K.-P. Hopfner, T. Carell
Proc. Natl. Acad. Sci. USA, 2010, 107, 20720-20725.
Mechanism of replication blocking and bypass of Y-family polymerase η by bulky acetylaminofluorene DNA adducts
121 M. Münzel, L. Lercher, M. Müller, T. Carell
Nucleic Acids Res. 2010, 38, e192.
Chemical discrimination between dC and 5MedC via their hydroxylamine adducts
120 S. Schneider, T. Reissner, O. Ziv, Z. Livneh, T. Carell
Chembiochem, 2010, 11, 1521-4.
Translesion synthesis of 1,3-GTG cisplatin DNA lesions
119 T. Brückl, I. Thoma, A. J. Wagner, P. Knochel, T. Carell
Eur. J. Org. Chem. 2010, 2010, 6517-6519.
Efficient Synthesis of Deazaguanosine-Derived tRNA Nucleosides PreQ0, PreQ1, and Archaeosine Using the Turbo-Grignard Method
118 M. Münzel, D. Globisch, T. Brückl, M. Wagner, V. Welzmiller, S. Michalakis, M. Müller, M. Biel, T. Carell
Angew. Chem. Int. Ed. 2010, 49, 5375-5377.
(Selected as Hot Paper and Highlighted in a Science and Technology Concentrate in Chem. Eng. News 2010, 88 (No 27), 24.)
Quantification of the Sixth DNA Base Hydroxymethylcytosine in the Brain
117 G. H. Clever, J. Reitmeier, T. Carell, O. Schiemann
Angew. Chem. Int. Ed. 2010, 49, 4927-4929.
(Selected as Hot Paper and Highlighted in a Science and Technology Concentrate in Chem. Eng. News 2010, 88 (No 27), 24.)
Antiferromagnetic Coupling of Stacked CuII-Salen Complexes in DNA
116 M. Winnacker, V. Welzmiller, R. Strasser, T. Carell
Chembiochem, 2010, 11, 1345-1349.
Development of a DNA Photoaffinity Probe for the Analysis of 8-OxodG-Binding Proteins in a Human Proteome
115 A. Schlossbauer, S. Warncke, P. E. Gramlich, J. Kecht, A. Manetto, T. Carell, T. Bein
Angew. Chem. Int. Ed. 2010, 49, 4734-4737.
A Programmable DNA-Based Molecular Valve for Colloidal Mesoporous Silica
114 K. Gutsmiedl, D. Fazio, T. Carell
Chemistry, 2010, 16, 6877-6883.
High-Density DNA Functionalization by a Combination of Cu-Catalyzed and Cu-Free Click Chemistry
113 T. Reißner, S. Schneider, S. Schorr, T. Carell
Angew. Chem. Int. Ed. 2010, 49, 3077-3080.
Crystal Structure of a Cisplatin-(1,3-GTG) Cross-Link within DNA Polymerase η

112 A. F. Glas, E. Kaya, S. Schneider, K. Heil, D. Fazio, M. J. Maul, T. Carell
J. Am. Chem. Soc. 2010, 132, 3254-3255.
DNA (6-4) Photolyases Reduce Dewar Isomers for Isomerization into (6-4) Lesions
111 E. Kaya, K. Gutsmiedl, M. Vrabel, M. Müller, P. Thumbs, T. Carell
Chembiochem, 2009, 10, 2858-2861.
Synthesis of threefold glycosylated proteins using click chemistry and genetically encoded unnatural amino acids
110 B. M. Gaub, C. Kaul, J. L. Zimmermann, T. Carell, H. E. Gaub
Nanotechnology, 2009, 20, 434002.
Switching the mechanics of dsDNA by Cu salicylic aldehyde complexation
109 A. F. Glas, S. Schneider, M. J. Maul, U. Hennecke, T. Carell
Chemistry, 2009, 15, 10387-10396.
Crystal Structure of the T(6-4)C Lesion in Complex with a (6-4) DNA Photolyase and Repair of UV-Induced (6-4) and Dewar Photolesions

108 A. F. Glas, M. J. Maul, M. Cryle, T. R. M. Barends, S. Schneider, E. Kaya, I. Schlichting, T. Carell
Proc. Natl. Acad. Sci. USA, 2009, 106, 11540-11545.
The archaeal cofactor F0 is a light-harvesting antenna chromophore in eukaryotes
107 C. Trindler, A. Manetto, J. Eirich, T. Carell
Chem. Commun. (Camb.) 2009, 24,3583-3584.
A new ground state single electron donor for excess electron transfer studies in DNA
106 K. Gutsmiedl, C. T. Wirges, V. Ehmke, T. Carell
Org. Lett. 2009, 11,2405-2408.
Copper-Free "Click" Modification of DNA via Nitrile Oxide-Norbornene 1,3-Dipolar Cycloaddition
105 M. Müller, T. Carell
Curr. Opin. Struct. Biol. 2009, 19,277-285.
Structural biology of DNA photolyases and cryptochromes
104 S. Warncke, A. Gégout, T. Carell
Chembiochem, 2009, 10,728-734.
Phosphorothioation of Oligonucleotides Strongly Influences the Inhibition of Bacterial (M.HhaI) and Human(Dnmt1) DNA Methyltransferases
103 S. Shachar, O. Ziv, S. Avkin, S. Adar, J. Wittschieben, T. Reißner, S. Chaney, E. C. Friedberg, Z. Wang, T. Carell, N. Geacintov, Z. Livneh
EMBO J. 2009, 28,383-393.
Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals
102 S. Schneider, S. Schorr, T. Carell
Curr. Opin. Struct. Biol. 2009, 19,87-95.
Crystal structure analysis of DNA lesion repair and tolerance mechanisms
101 M. Winnacker, S. Breeger, R. Strasser, T. Carell
Chembiochem, 2009, 10,109-118.
Novel Diazirine-Containing DNA Photoaffinity Probes for the Investigation of DNA-Protein-Interactions
100 T. Brückl, D. Globisch, M. Wagner, M. Müller, T. Carell
Angew. Chem. Int. Ed. 2009, 48,7932-7934.
(Selected as Hot Paper and Highlighted in a Science and Technology Concentrate in Chem. Eng. News, 2009, 87 (No 38), 35.)
Parallel Isotope-Based Quantification of Modified tRNA Nucleosides
99 T. Reißner, S. Schorr, T. Carell
Angew. Chem. Int. Ed. (Highlight), 2009, 48,7293-7295.
Once Overlooked, Now Made Visible: ATL Proteins and DNA Repair
98 C. T. Wirges, J. Timper, M. Fischler, A. S. Sologubenko, J. Mayer, U. Simon, T. Carell
Angew. Chem. Int. Ed. (Highlight), 2009, 48,219-223.
Controlled Nucleation of DNA Metallization
97 R. Pokorny, T. Klar, U. Hennecke, T. Carell, A. Batschauer, L. O. Essen
Proc. Natl. Acad. Sci. USA, 2008, 105,21023-21027.
Recognition and repair of UV lesions in loop structures of duplex DNA by DASH-type cryptochrome
96 E. Bürckstümmer, T. Carell
Chem. Commun. (Camb). 2008, 34,4037-4039.
Synthesis and properties of DNA containing a spore photoproduct analog
95 F. Coste, M. Ober, Y.-V. Le Bihan, M. A. Izquierdo, N. Hervouet, H. Mueller, T. Carell, B. Castaing
Chem. Biol. 2008, 15,706-717.
Bacterial Base Excision Repair Enzyme Fpg Recognizes Bulky N7-Substituted-FapydG Lesion via Unproductive Binding Mode
94 H. Müller, M. Hopfinger, T. Carell
Chembiochem, 2008, 9,1617-1622.
Synthesis of a Stabilized Version of the Imidazolone DNA Lesion
93 P. M. E. Gramlich, C. T. Wirges, J. Gierlich, T. Carell
Org. Lett. 2008, 10,249-251.
Synthesis of Modified DNA by PCR with Alkyne-Bearing Purines Followed by a Click Reaction
92 M. Fischler, A. Sologubenko, J. Mayer, G. Clever, G. A. Burley, J. Gierlich, T. Carell, U. Simon
Chem. Commun. (Camb.) 2008, 169-171.
Chain-like assembly of gold nanoparticles on artificial DNA templates via "click chemistry"
91 M. J. Maul, T. R. M. Barends, A. F. Glas, M. J. Cryle, T. Domratcheva, S. Schneider, I. Schlichting, T. Carell
Angew. Chem. Int. Ed. 2008, 47,10076-10080.
Crystal Structure and Mechanism of a DNA (6-4) Photolyase

90 P. M. E. Gramlich, C. T. Wirges, A. Manetto, T. Carell
Angew. Chem. Int. Ed. 2008, 47,8350-8358.
Postsynthetic DNA Modification through the Copper-Catalyzed Azide-Alkyne Cycloaddition Reaction
89 P. M. E. Gramlich, S. Warncke, J. Gierlich, T. Carell
Angew. Chem. Int. Ed., 2008, 47,3442-3444.
Click-Click-Click: Single to Triple Modification of DNA
88 D. Kuch, L. Schermelleh, S. Manetto, H. Leonhardt, T. Carell
Angew. Chem. Int. Ed., 2008, 47,1515-1518.
Synthesis of DNA Dumbbell Based Inhibitors for the Human DNA Methyltransferase Dnmt1
87 S. Bareyt, T. Carell
Angew. Chem. Int. Ed., 2008, 47,181-184.
Selective Detection of 5-Methylcytosine Sites in DNA
86 F. Büsch, J. C. Pieck, M. Ober, J. Gierlich, G. W. Hsu, L. S. Beese, T. Carell
Chemistry, 2008, 14,2125-2132.
Dissecting the Differences between the αand β Anomers of the Oxidative DNA Lesion FaPydG
85 T. Brückl, F. Klepper, K. Gutsmiedl, T. Carell
Org. Biomol. Chem. 2007, 5,3821-3825.
A short and efficient synthesis of the tRNA nucleosides PreQ0 and archaeosine
84 G. E. Damsma, A. Alt, F. Brueckner, T. Carell, P. Cramer
Nat. Struct. Mol. Biol. 2007, 14,1127-1133.
Mechanism of transcriptional stalling at cisplatin-damaged DNA
83 A. Alt, K. Lammens, C. Chiocchini, A. Lammens, J. C. Pieck, D. Kuch, K.-P. Hopfner, T. Carell
Science, 2007, 318,967-970.
Bypass of DNA lesions generated during anticancer treatment with cisplatin by DNA polymerase η
82 D. I. Rozkiewicz, J. Gierlich, G. A. Burley, K. Gutsmiedl, T. Carell, B. J. Ravoo, D. N. Reinhoudt
Chembiochem, 2007, 8,1997-2002.
Transfer Printing of DNA by "Click" Chemistry
81 M. Fischler, U. Simon, H. Nir, Y. Eichen, G. A. Burley, J. Gierlich, P. M. E. Gramlich, T. Carell
Small. 2007, 3, 1049-1055.
Formation of Bimetallic Ag-Au Nanowires by Metallization of Artificial DNA Duplexes
80 A. Manetto, D. Georganakis, L. Leondiadis, T. Gimisis, P. Mayer, T. Carell, C. Chatgilialoglu
J. Org. Chem. 2007, 72, 3659-3666.
Independent Generation of C5′-Nucleosidyl Radicals in Thymidine and 2′-Deoxyguanosine
79 C. T. Wirges, P. M. E. Gramlich, K. Gutsmiedl, J. Gierlich, G. A. Burley, T. Carell
QSAR Comb. Sci. 2007, 26, 1159-1164.
Pronounced Effect of DNA Hybridization on Click Reaction Efficiency
78 F. Spada, A. Haemmer, D. Kuch, U. Rothbauer, L. Schermelleh, E. Kremmer, T. Carell, G. Längst, H. Leonhardt
J. Cell. Biol. 2007, 176, 565-571.
DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells
77 F. Brueckner, U. Hennecke, T. Carell, P. Cramer
Science, 2007, 315, 859-862.
CPD Damage Recognition by Transcribing RNA Polymerase II
76 H. Müller, T. Carell
Eur. J. Org. Chem. 2007, 9, 1438-1445.
A Carbocyclic Analog of the Oxidatively Generated DNA Lesion Spiroiminodihydantoin
75 W. J. Schreier, T. E. Schrader, F. O. Koller, P. Gilch, C. E. Crespo-Hernández, V. N. Swaminathan, T. Carell, W. Zinth, B. Kohler
Science, 2007, 315, 625-629.
Thymine Dimerization in DNA is an Ultrafast Photoreaction
74 G. H. Clever, C. Kaul, T. Carell
Angew. Chem. Int. Ed. 2007, 46, 6226-6236.
DNA-metal base pairs
73 D. M. Hammond, A. Manetto, J. Gierlich, V. A. Azov, P. M. E. Gramlich, G. A. Burley, M. Maul, T. Carell
Angew. Chem. Int. Ed. 2007, 46, 4184-4187.
DNA Photography: An Ultrasensitive DNA-Detection Method Based on Photographic Techniques
72 U. Hennecke, D. Kuch, T. Carell
Synthesis, 2007, 6, 929-935.
A General Route to 4-C-Substituted Pyrimidine Nucleosides
71 F. Klepper, E.-M. Jahn, V. Hickmann, T. Carell
Angew. Chem. Int. Ed. 2007, 46, 2325-2327.
Synthesis of the Transfer-RNA Nucleoside Queuosine by Using a Chiral Allyl Azide Intermediate
70 G. H. Clever, T. Carell
Angew. Chem. Int. Ed. 2007, 46, 250-253.
Controlled Stacking of 10 Transition-Metal Ions inside a DNA Duplex
69 J. Gierlich, K. Gutsmiedl, P. M. E. Gramlich, A. Schmidt, G. A. Burley, T. Carell
Chemistry, 2007, 13, 9486-9494.
Synthesis of Highly Modified DNA by a Combination of PCR with Alkyne-Bearing Triphosphates and Click Chemistry
68 C. Chatgilialoglu, M. Guerra, P. Kaloudis, C. Houée-Lévin, J. L. Marignier, V. N. Swaminathan, T. Carell
Chemistry, 2007, 13, 8979-8984.
Ring Opening of the Cyclobutane in a Thymine Dimer Radical Anion
67 K. Tanaka, G. H. Clever, Y. Takezawa, Y. Yamada, C. Kaul, M. Shionoya, T. Carell
Nature Nanotechnol. 2006, 1, 190-194.
Programmable self-assembly of metal ions inside artificial DNA duplexes
66 K. Tanaka, G. H. Clever, Y. Takezawa, Y. Yamada, C. Kaul, M. Shionoya, T. Carell
Nature Nanotechnol. 2006, 1, 190-194.
Programmable self-assembly of metal ions inside artificial DNA duplexes
65 G. H. Clever, Y. Soltl, H. Burks, W. Spahl, T. Carell
Chemistry, 2006, 12, 8708.
Metal-Salen-Base-Pair Complexes Inside DNA: Complexation Overrides Sequence Information
64 J. C. Pieck, U. Hennecke, A. J. Pierik, M. G. Friedel, T. Carell
J. Biol. Chem. 2006, 281, 36317.
Characterization of a New Thermophilic Spore Photoproduct Lyase from Geobacillus stearothermophilus (SplG) with Defined Lesion Containing DNA Substrates
63 T. Klar, G. Kaiser, U. Hennecke, T. Carell, A. Batschauer, L. O. Essen
Chembiochem, 2006, 7, 1798.
Natural and Non-natural Antenna Chromophores in the DNA Photolyase from Thermus Thermophilus
62 S. Breeger, M. von Meltzer, U. Hennecke, T. Carell
Chemistry, 2006, 12, 6469-6477.
Investigation of the pathways of excess electron transfer in DNA with flavin-donor and oxetane-acceptor modified DNA hairpins
61 J. Gierlich, G. A. Burley, P. M. E. Gramlich, D. M. Hammond, T. Carell
Org. Lett. 2006, 8, 3639-3642.
Click Chemistry as a Reliable Method for the High-Density Postsynthetic Functionalization of Alkyne-Modified DNA
60 M. G. Friedel, J. C. Pieck, J. Klages, C. Dauth, H. Kessler, T. Carell
Chemistry, 2006, 12, 6081-6094.
Synthesis and Stereochemical Assignment of DNA Spore Photoproduct Analogues
59 J. C. Pieck, D. Kuch, F. Grolle, U. Linne, C. Haas, T. Carell
J. Am. Chem. Soc. 2006, 128, 1404-1405.
PNA-Based Reagents for the Direct and Site-Specific Synthesis of Thymine Dimer Lesions in Genomic DNA
58 G. A. Burley, J. Gierlich, M. R. Mofid, H. Nir, S. Tal, Y. Eichen, T. Carell
J. Am. Chem. Soc. 2006, 128, 1398-1399.
Directed DNA Metallization
57 M. G. Friedel, O. Berteau, J. C. Pieck, M. Atta, S. Ollagnier-de-Choudens, M. Fontecave. T. Carell
Chem. Commun. (Camb.) 2006, 445-447.
The spore photoproduct lyase repairs the 5S- and not the 5R-configured spore photoproduct DNA lesion
56 M. Ober, H. Müller, C. Pieck, J. Gierlich, T. Carell
J. Am. Chem. Soc. 2005, 127, 18143-18149.
Base Pairing and Replicative Processing of the Formamidopyrimidine-dG DNA Lesion
55 A. Manetto, S. Breeger, C. Chatgilialoglu, T. Carell
Angew. Chem. Int. Ed. 2005, 45, 318-321.
Complex Sequence Dependence by Excess-Electron Transfer through DNA with Different Strength Electron Acceptors
54 G. H. Clever, K. Polborn, T. Carell
Angew. Chem. Int. Ed. 2005, 44, 7204-7208.
A Highly DNA-Duplex-Stabilizing Metal-Salen Base Pair
53 F. Klepper, K. Polborn, T. Carell
Helv. Chim. Acta, 2005, 88, 2610-2616.
Robust synthesis and crystal-structure analysis of 7-cyano-7-deazaguanine (PreQ0 base) and 7-(aminomethyl)-7-deazaguanine (PreQ1 base)
52 M. G. Friedel, M. K. Cichon, T. Carell
Org. Biomol. Chem. 2005, 3, 1937-1941.
Model compounds for (6-4) photolyases: a comparative flavin induced cleavage study of oxetanes and thietanes
51 M. v. Meltzer, M. Marsch, T. Carell, K. Harms
Acta. Cryst. E. 2005, 3, 1937-1941.
(1S,2R,4R,5R)-tert-Butyl N-(4-hydroxymethyl-6-oxabicyclo[3.1.0]hex-2-yl)carbamate
50 A. Mees, T. Klar, P. Gnau, U. Hennecke, A. P. M. Eker, T. Carell and L.-O. Essen
Science, 2004, 306, 1789-1793.
Crystal Structure of a Photolyase Bound to a CPD-Like DNA Lesion After in Situ Repair
49 L. M. Kundu, U. Linne, M. Marahiel, T. Carell
Chemistry, 2004, 10, 5697-5705.
RNA Is More UV Resistant than DNA: The Formation of UV-Induced DNA Lesions is Strongly Sequence and Conformation Dependent
48 F. Coste, M. Ober, T. Carell, S. Boiteux, C. Zelwer, and B. Castaing
J. Biol. Chem. 2004, 279, 44074-44083.
Structural Basis for the Recognition of the FapydG Lesion (2,6-Diamino-4-hydroxy-5-formamidopyrimidine) by Formamidopyrimidine-DNA Glycosylase
47 G. W. Hsu, M. Ober, T. Carell, L. S. Beese
Nature, 2004, 431, 217-221.
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase
46 M. v. Meltzer, M. Marsch, T. Carell and K. Harms
Acta. Cryst. E. 2004, E60, 2515-2516.
(1S,2R,4S,5R)-tert-Butyl 7-oxo-3-oxa-6-azatricyclo[,4]octane-6-carboxylate
45 B. Giese, B. Carl, T Carl, T. Carell, C. Behrens, U. Hennecke, O. Schiemann, E. Feresin
Angew. Chem. Int. Ed., 2004, 43, 1848-1851.
Excess electron transport through DNA: A single electron repairs more than one UV-induced lesion
44 C. Behrens, M. Cichon, F. Grolle, U. Hennecke, T. Carell
Top. Curr. Chem. 2004, 236, 187-204.
Excess electron transfer in defined donor-nucleobase and donor-DNA-acceptor systems
43 M. Ober, M.Marsch, K. Harms, T. Carell
Act. Cryst. E. 2004, E60, o1191-o1192.
A carbocyclic analogue of a protected a-D-2-deoxyribosylamine
42 C. Haas, K. Kräling, M. Cichon, N. Rahe and T. Carell
Angew. Chem. Int. Ed. 2004, 43, 1842-1844.
Excess electron transfer driven DNA repair does not depend on the transfer direction
41 S. Breeger, U. Hennecke and T. Carell
J. Am. Chem. Soc. 2004, 126, 1302-1303.
Excess Electron Transfer Based Repair of a cis-syn Thymine Dimer in DNA is only Weakly Sequence Dependent
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Philipps-Universität Marburg (Germany):
40 M. Ober, U. Linne, J. Gierlich, T. Carell
Angew. Chem. Int. Ed. 2003, 42, 4947-4951.
The two main oxydative DNA lesions 8-oxo-7,8-dihydroguanine and 2,6-diamino-5-formamido-4-hydroxypyrimidine exhibit strongly different pairing characteristics
39 N. Rahe, C. Rinn, T. Carell
Chem. Commun. (Camb.) 2003, 2120-2121.
Development of Donor/Acceptor Modified DNA Hairpins for the Investigation of Charge Hopping Kinetics in DNA
38 A. Mees, C. Behrens, A. Schwögler, M. Ober, T. Carell
Eur. J. Org. Chem. 2003, 2670-2677.
Redoxactive Oligonucleotides: Synthesis and Properties of Flavocoenzyme-DNA
37 C. Behrens, T. Carell
Chem. Commun. (Camb.) 2003, 1632-1633.
Excess Electron Transfer in Flavin-Capped, Thymine Dimer-Containing DNA Hairpins
36 T. Carell, C. Behrens, J. Gierlich
Org. Biomol. Chem. 2003, 1 2221-2228.
Electron transfer Through DNA and Metal-Containing DNA
35 M. Cichon, C. Haas, F. Grolle, A. Mees, T. Carell
J. Am. Chem. Soc. 2002, 124 13984-13985.
Efficient Interstrand Excess Electron Transfer in PNA:DNA Hybrids
34 L. Kundu, L. Burgdorf, T. Carell
Chembiochem, 2002, 3 1053-1060.
Thymine Dimer Containing Molecular Beacons for the Investigation of Photolyase Activity in Cell Extracts
33 C. Behrens, M.Ober, T. Carell
Eur. J. Org. Chem. 2002, 3 3281-3289.
Flavin-Capped DNA Hairpins for Excess Electron Transfer Studies in DNA
32 C. Behrens, L. Burgdorf, A. Schwögler, T. Carell
Angew. Chem. Int. Ed. 2002, 41 1763-1766.
Shallow distance dependence of excess electron transfer through DNA
31 M. Cichon, S. Arnold, T. Carell
Angew. Chem. Int. Ed. 2002, 41 767-770.
Repair of the oxetane lesion by (6-4) DNA photolyases requires a reduced and deprotonated flavin
30 L. Burgdorf, T. Carell
Chemistry, 2002, 8 293-301.
Synthesis, stability, and conformation of the Formamidopyrimidine G DNA lesion
29 T. Carell, L. Burgdorf, L. Kundu
Curr. Opin. Chem. Biol. 2001, 5 491-498.
The Mechanism of Action of Photolyase
28 D. Nikova, B. de Frooth, K. Groener, C. Wyman, A. Eker, T. Carell, J. Greve
Biophys. J. 2000, 78 1552.
Specific and non-specific interactions in DNA repair processes
27 A. Schwögler, L. Burgdorf, T. Carell
Angew. Chem. Int. Ed. 2000, 39 3918-3920.
Self-Repairing DNA Based on a Reductive Electron Transfer Through the Base Stack
26 A. Schwögler, T. Carell
Helv. Chim. Acta. 2000, 83 2452-2463.
Synthesis and Properties of Flavin Nucleosides
25 A. Schwögler, T. Carell
Org. Lett. 2000, 2 1415-1418.
Towards Catalytically Active Oligonucleotides: Synthesis and Properties of a Flavin Nucleotide and its Incorporation in DNA
24 J. Butenandt, R. Epple, E.-U. Wallenborn, A. Eker, V. Gramlich, T. Carell
Chemistry, 2000, 6 62-72.
DNA-Photolyase Models: A Comparative Cleavage Study With Cyclobutane Uracil- and Thyminedimer Model Compounds
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ETH-Zürich (Switzerland):
23 O. Kleiner, J. Butenandt, T. Carell, A. Batschauer
Eur. J. Biochem. 1999, 264, 161-167.
Class II DNA photolyase from Arabidopsis thaliana contains FAD as cofactor
22 J. Butenandt, L. T. Burgdorf, T. Carell
Synthesis, 1999, 1085-1105.
Synthesis of DNA Lesions and DNA-Lesion-Containing Oligonucleotides For DNA-Repair Studies
21 R. Epple, T. Carell
J. Am. Chem. Soc. 1999, 121, 7318-7329.
Efficient Light Dependent DNA-Repair Requires a Large Cofactor Separation
20 J. Butenandt, L. Burgdorf, T. Carell
Angew. Chem. Int. Ed. 1999, 38, 708-711.
"Base Flipping": Photodamaged DNA-RNA Duplexes Are Poor Substrates for Photoreactivating DNA-Repair Enzymes
19 T. Carell, H. Schmid, M. Reinhard
J. Org. Chem. 1998, 63, 8741-8747.
A Convenient Synthesis of a Flavin- and a Deazaflavin-Amino Acid and their Incorporation into Oligopeptides
18 T. Carell, R. Epple
Eur. J. Org. Chem. 1998, 7, 1245-1248.
Repair of UV-light Induced DNA Lesions: A Comparative Study with Model Compounds
17 R. Epple, T. Carell
Angew. Chem. Int. Ed. 1998, 37, 938-941.
Flavin and Deazaflavin Containing Model Compounds Mimic the Energy-Transfer Step in Type II DNA-Photolyases
16 J. Butenandt, A. P. M. Eker, T. Carell
Chemistry, 1998, 4, 642-654.
Synthesis, Crystal-Structure and Enzymatic Evaluation of a DNA-Photolesion Isostere
15 T. Carell, R. Epple, V. Gramlich
Helv. Chim. Acta, 1997, 80, 2191-2203.
Synthesis and Structure of (Carboxymethyl)-Functionalized Cyclobuta-Fused Uracil Dimers
14 R. Epple, E.-U. Wallenborn, T. Carell
J. Am. Chem. Soc. 1997, 119, 7440-7451.
Investigation of Flavin-Containing DNA-Repair Model Compounds
13 T. Carell, J. Butenandt
Angew. Chem. Int. Ed. 1997, 36, 1461-1464.
Towards Artificial DNA-Repair Enzymes: Incorporation of a Flavin Amino Acid into DNA-Binding Oligopeptides
12 T. Carell, R. Epple, V. Gramlich
Angew. Chem. Int. Ed. 1996, 35, 620-623.
Towards Artificial DNA-Repair Enzymes: Incorporation of a Flavin Amino Acid into DNA-Binding Oligopeptides
11 T. Carell
Angew. Chem. Int. Ed. 1995, 34, 2491-2494.
Sunlight-Damaged DNA Repaired with Sunlight
10 T. Carell
Chimia, 1995, 49, 365-373.
Sunlight-Induced DNA Lesions. Lesion Structure, Mutation Characteristics and Repair
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MIT (Cambridge, USA):
9 A. S. Fang, P. Vouros, C. C. Stacey, G. H. Kruppa, F. H. Laukien, E. A. Wintner, T. Carell, J. Rebek
Comb. Chem. & High Throughput Screening. 1998, 23-33.
Rapid characterization of combinatorial libraries using electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry
8 E. A. Wintner, J. Shipps, T. Carell, J. Rebek, Y. Dunayevskiy, P. Vouros
Proc. Natl. Acad. Sci. USA, 1996, 93, 6152-6157.
Application of Capillary Electrophoresis-Electrospray Ionization Mass Spectrometry in the Determination of Molecular Diversity
7 T. Carell, E. A. Wintner, J. Rebek, Jr., Y. Dunayevskiy, P. Vouros
Anal. Chem. 1995, 67, 2906-2915.
Characterization of the Complexity of Small-Molecule Libraries by Electrospray Ionization Mass Spectrometry
6 T. Carell, E. A. Wintner, A. J. Sutherland, J. Rebek, Jr., Y. M. Dunayevskiy, P. Vouros
Chem. Biol. 1995, 2, 171-183.
New Promise in Combinatorial Chemistry: Synthesis, Characterization, and Screening of Small-Molecule Libraries in Solution
5 T. Carell, E. A. Wintner, J. Rebek, Jr.
Angew. Chem. Int. Ed. 1994, 33, 2061-2064.
A Solution-Phase Screening Procedure for the Isolation of Active Compounds from a Library of Molecules
4 T. Carell, E. A. Wintner, A. Bashir-Hashemi, J. Rebek, Jr.
Angew. Chem. Int. Ed. 1994, 33, 2059-2061.
A Novel Procedure for the Synthesis of Libraries Containing Small Organic Molecules
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Max-Planck-Institut for Medical Research (Heidelberg, Germany):
3 H. A. Staab, T. Carell
Angew. Chem. Int. Ed. 1994, 33, 1466-1468.
Synthesis and Properties of a Vertically Stacked Porphyrin1-Porphyrin2-Quinone Cyclophane
2 H. A. Staab, T. Carell, A. Döhling
Chem. Ber. 1994, 127, 223-229.
Syntheses and Properties of New Quinone-Bridged Diphenyl- and Tetraphenylporphyrins
1 C. Krieger, M. Dernbach, G. Voit, T. Carell, H. A. Staab
Chem. Ber. 1993, 126, 811-821.
Conformational Mobility and Crystal Structures of Porphyrin-Quinone Cyclophanes
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Other publications and activity:
16 T. Carell
Angew. Chem. Int. Ed. 2015, doi:10.1002/anie.201509770
DNA Repair.
15 E. Parsa, A. Schröder, T. Carell
Naturwissenschaftliche Rundschau 2015, 3, 128-133.
Modifizierte DNA-Basen erweitern das Verständnis der Genregulation
14 T. Carell
Curr. Opin. Struct. Biol. 2012, 22, 689-90
Catalysis and regulation
13 T. Carell
Nature (News & Views). 2011, 469, 45-46.
Molecular computing: DNA as a logic operator
12 J. Cadet, T. Carell, L. Cellai, C. Chatgilialoglu, T. Gimisis, M. Miranda, P. O'Neill, J.-L. Ravanat, M. Robert
Chimia, 2008, 62, 742-749.
DNA damage and radical reactions: mechanistic aspects, formation in cells and repair studies
11 T. Carell, P. Cramer, K.-H. Hopfner
Nucleic Acids Symp. Ser. 2008, 15, 103.
The chemistry of transcription through damaged DNA and of translesion synthesis at atomic resolution
10 M. Friedel, M. K. Cichon, T. Carell
CRC Handbook of Photochemistry and Photobiology 2004, 141/1-141/22.
DNA Repair: Photochemistry
9 T. Carell
Nature 2004, 431, 398.
German reform would make little difference
8 P. H. Seeberger, T. Carell
Curr. Opin. Chem. Biol. 2003, 7, 715-716.
Org. Biomol. Chem. 2003, 1, XI.
Profile Thomas Carell
6 T. Carell
Chemie Heute. 2000 ⁄ 2001, 102-105.
Damit unser Erbgut intakt bleibt
Verschiedene Beiträge zur Darstellung der Jungen Akademie
Organisation des 8. Nachwuchswissenschaftler Symposiums "Bioorganische Chemie", Heidelberg 20.-22. September 1999
Chimia, 1997, 12, 952-962.
Conference report about the 36. IUPAC Congress: Frontiers in Chemistry, New Perspectives for the 2000s
Nachr Chem Tech Lab. 1996, 44, 713-715.
Conference report about the 31. Euchem-Conference on Stereochemistry, Bürgenstock, Switzerland, 1996. "Ein Blick in die Zukunft der Chemie"
Angew. Chem. 1996, 108, 990-991try, Book Report: G. Quinkert, E. Egert, C. Griesinger, Aspekte der Organischen Chemie, Struktur, Verlag Helv. Chim. Acta, Basel 1995