Prof. Dr. Franz Bracher

Chair of Pharmaceutical/Medicinal Chemistry

	Address	Prof. Dr. Franz Bracher Department Pharmazie - Zentrum für Pharmaforschung - Ludwig-Maximilians-Universität München Butenandtstr. 7, Haus C 81377 München Germany
	Office	+49 (0)89 2180-77300 (Melanie Pfoser)
	Phone	+49 (0)89 2180-77301
	Fax	+49 (0)89 2180-77802
	Room	C3.054
	E-Mail	franz.bracher@cup.uni-muenchen.de melanie.pfoser@cup.uni-muenchen.de
	Internet	Webseite

• Natural product chemistry (synthesis, biological activities)
• Inhibitors of ergosterol and cholesterol biosynthesis as new drugs
• Development of new, selective kinase inhibitors

• Studied pharmacy at the LMU Munich
• 1986 PhD in Pharmaceutical Chemistry, LMU Munich
• 1986-1987 Postdoctoral Researcher at the Department of Organic Chemistry, University of Geneve/Switzerland
• 1991 Habilitation, University of Marburg
• 1992-1997 C3 Professor, University of Braunschweig
• Since 1997 C4 Professor for Pharmaceutical Chemistry, LMU Munich

• O. Fedorov, K. Huber, A. Eisenreich, P. Filippakopoulos, O. King, A. N. Bullock, D. Fabro, J. Trappe, U. Rauch, F. Bracher, S. Knapp: Specific CLK inhibitors from a novel chemotype for regulation of alternative splicing, Chemistry and Biology (2011), 18, 67-76
• K. Huber, J. Schemies, U. Uciechowska, J. M. Wagner, T. Rumpf, F. Lewrick, R. Süss, W. Sippl, M. Jung, F. Bracher: Novel 3-arylidene-indolin-2-ones as inhibitors of NAD+-dependent histone deacetylases (sirtuins) J. Med. Chem. (2010), 53, 1383
• D. Renard, J. Perruchon, M. Giera, J. Müller, F. Bracher: Side chain azasteroids and thiasteroids as sterol methyltransferase inhibitors in ergosterol biosynthesis, Bioorg. Med. Chem. (2009) 17, 8123-8137