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Dr. Martina Rüffer

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Dr. Martina Rüffer
Department Pharmazie
- Zentrum für Pharmaforschung -
Ludwig-Maximilians-Universität München
Butenandtstr. 5-13, Haus D
81377 München
Germany

Phone +49 (0)89 2180-77052
Fax +49 (0)89 2180-77791
Room D3.021
E-Mail Martina.Rueffer@cup.uni-muenchen.de
Internet Webseite
Research interests
  • Development of nonviral vectors
  • Purification of polyplexes
Short CV
  • 1974 Diploma in Biology, Ruhr-Universität Bochum,Topic: End group analysis of Laccases from Podospora anserina
  • 1977 Ph.D (Dr. rer. nat.), Ruhr-Universität Bochum, Topic: Studies in the biosynthesis of phenylpropanoid natural products
  • Since 1980 Ludwig-Maximilians-Universität München, Department Pharmazie, Pharmaceutical Biology, Akademische Oberrätin
Key publications
  • Rueffer, M., Zenk, M.H. (1998) Microsome-mediated transformation of O-methylandrocymbine to demecolcine and colchicine. FEBS Lett 438, 111-113. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9821969&dopt=Abstract
  • Rueffer, M. and M.H. Zenk : Enzymatic formation of protopines by a microsomal cytochrome P-450 system of Corydalis vaginans Tetrahedron Lett., 28, (1987), 5307-5310.
  • Rüffer, M., N. Nagakura, M.H. Zenk: Strictosidine, the common precursor for monoterpenoid indole alkaloids with 3 a-and 3ß-configuration. Tetrahedron Letters 18, (1978), 1593-1596.