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Inhaltsbereich

Dr. Manfred Ogris

Development of non-Viral Gene Transfer Vectors

Address

Dr. Manfred Ogris
Department Pharmazie
- Zentrum für Pharmaforschung -
Ludwig-Maximilians-Universität München
Butenandtstr. 5-13, Haus D
81377 München
Germany

Phone +49 (0)89 2180-77842
Fax +49 (0)89 2180-77791
Room D3.026
E-Mail Manfred.Ogris@cup.uni-muenchen.de
Internet Webseite
Research interests
  • Cancer gene therapy
  • Targeted nucleic acid delivery
  • Thermoinducible delivery systems
Short CV
  • Studied Biotechnology at the University of Natural Resources and Applied Life Sciences (BOKU), Vienna/Austria
  • 1999 Ph.D. Vienna/Austria
  • 1999-2000 Postdoctoral Researcher, Institute for Cancer Research, Birmingham/UK
  • 2000-2001 Marie Curie Fellow, Institute for Cancer Research, Birmingham/UK
  • Since 2001 Group Leader, LMU Munich
Key publications
  • de Bruin, K., Ruthardt, N., von Gersdorff, K., Bausinger, R., Wagner, E., Ogris, M., and Braeuchle, C. (2007) Cellular dynamics of EGF receptor-targeted synthetic viruses. Mol. Ther. 15(7), 1297-1305.
  • Boeckle, S., von Gersdorff, K., van der Piepen, S., Culmsee, C., Wagner, E., and Ogris, M. (2004) Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer. J. Gene Med. 6, 1102-1111.
  • Ogris M, Brunner S, Schueller S, Kircheis R and Wagner E (1999) PEGylated DNA/Transferrin-PEI complexes: Reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery. Gene Therapy 6, 595-605.