Dr. Dierk Niessing
Motor Protein-dependent Transport of Cellular Cargo
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Address | Dr. Dierk Niessing Department Chemie und Genzentrum München Ludwig-Maximilians-Universität München Feodor-Lynen-Str. 25 81377 München Germany |
| Phone | +49 (0)89 2180-76962 | |
| Fax | +49 (0)89 2180-76962 | |
| Room | A4.065 | |
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niessing@genzentrum.lmu.de niessing@helmholtz-muenchen.de | ||
| Internet | Webseite |
Research interests
- Assembly and function of motor-protein dependent translocation complexes that transport RNAs, vesicles and organelles through the cytoplasm.
- We apply X-ray crystallography, biophysical, biochemical, and collaborative in vivo approaches.
Short CV
- 1990-1996 Studied Biology at the University of Göttingen
- 2000 PhD, Max-Planck Institute for Biophysical Chemistry, Göttingen
- 2000-2005 Postdoctoral research at Rockefeller University, NY/USA and at SGX-Pharmaceuticals, Inc, San Diego/USA
- Since 2005 Research group leader at the Gene Center, LMU Munich (jointly supported by the Helmholtz Zentrum München and the Gene Center)
Key publications
- Heuck, A., Du, T.-G., Jellbauer, S., Richter, K., Kruse, C., Jaklin, S., Müller, M., Buchner, J., Jansen, R.-P., and Niessing, D.: Monomeric myosin V uses two binding regions for the assembly of stable translocation complexes. Proc. Natl. Acad. Sci. USA - Track II: 105: 19778-19783 (2007) .
- Niessing, D., Zenklusen, D., Hüttelmaier, S., Singer, R.H. and Burley, S.K.: She2p is a Novel RNA-Binding Protein with a Basic Helical Hairpin Motif. Cell 119: 491-502 (2004).
- Niessing, D., Blanke, S.& Jäckle, H.: Bicoid associates with the 5'cap-bound complex of caudal mRNA and represses translation. Genes & Dev. 16: 2576-2582 (2002).
